Minoxidil 5 mg

Minoxidil is a synthetic small molecule belonging to the class of potassium channel openers, chemically a pyrimidine N-oxide derivative. In scientific research, it is studied as a model compound for ion channel biophysics and as a reference standard in analytical work. This compound is offered as 5 mg tablets, exclusively for laboratory and research purposes.

What is Minoxidil?

Minoxidil (2,4-diamino-6-piperidinopyrimidine-3-oxide) is a small organic molecule that belongs to the openers of ATP-sensitive potassium channels (K_ATP-channels). The structure combines a diaminopyrimidine core with a piperidine ring and an N-oxide function, an arrangement that makes the compound a widely used model in the study of potassium channel modulation and associated membrane biophysics.

In research models, Minoxidil itself serves as the starting compound: enzymatic conversion by sulfotransferases yields the sulfate metabolite minoxidil sulfate, the form that exhibits the strongest interaction with the potassium channel in vitro. This two-step biotransformation makes the compound interesting for enzymological and receptor-oriented laboratory research. Consequently, Minoxidil is used as a model compound and reference substance within scientific research.

Forskningsområden

In a laboratory context, Minoxidil occurs in the following research areas, among others:

• Research into ATP-sensitive potassium channels (K_ATP) and membrane hyperpolarization in isolated cell models in vitro.
• Enzymological investigation into the sulfotransferase-mediated conversion of Minoxidil to the metabolite minoxidil sulfate.
• Biophysical model studies on ion channel openers and the structure-activity relationship of pyrimidine N-oxide compounds.
• Model studies according to K_ATP-channel expression and receptor-ligand interaction in cell culture systems.
• Analytical method development and validation (HPLC, LC-MS) using Minoxidil as the reference standard.
• Stability and solubility studies of small, N-oxide-containing molecules under controlled conditions.

Var och en av dessa tillämpningar involverar kontrollerad laboratorie- eller preklinisk modellforskning.

Minoxidil in our research assortment

Minoxidil falls under the category of oral investigation compounds in solid tablet form within our range. Researchers working with this category frequently combine the compound with other small molecules that are studied via their own biochemical targets. While Minoxidil focuses on the modulation of ATP-sensitive potassium channels, other components within the same product line have been specifically chosen to cover various enzymatic or receptor-linked targets. These compounds share the oral tablet form but differ fundamentally in molecular class and investigated mechanism.

Specifikationer

Form, hantering och förvaring

Minoxidil is supplied as solid tablets with a standardized amount of 5 mg per tablet, packaged in quantities of 100. Unlike freeze-dried peptides, this solid form does not require reconstitution; the tablets can be weighed directly in a laboratory setup or, if necessary, dissolved in a suitable solvent for further analysis.

Store the tablets dry at room temperature, protected from direct light and moisture, in the original packaging. Observe the compound with the usual laboratory precautions: work in a clean environment, use suitable personal protective equipment, and prevent cross-contamination with other research materials. Keep the packaging out of reach of unauthorized persons.

Sammansättning och labresultat

For this compound, the content is expressed as the amount of active substance per tablet (5 mg per tablet) rather than as a purity percentage, as is customary for tablet and capsule formulations.

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Vanliga frågor

To which class of substances does Minoxidil belong?
Minoxidil is a small synthetic molecule (a pyrimidine N-oxide) from the class of ATP-sensitive potassium channel openers. It is not a peptide and therefore contains no amino acid sequence.

What is the role of minoxidil sulfate in research?
In research models, minoxidil is converted into minoxidil sulfate by sulfotransferase enzymes. This metabolite exhibits the strongest interaction with the potassium channel in vitro and is therefore a central focus of mechanistic and enzymological laboratory research.

I vilken form levereras föreningen?
As 5 mg tablets, packed in units of 100. The solid tablet form requires no reconstitution.

How do I store the tablets?
Dry, at room temperature and protected from light and moisture, preferably in the original packaging.

Avsedd uteslutande för laboratorie- och forskningsändamål. Ej för mänsklig eller animalisk konsumtion, eller för medicinsk, diagnostisk, terapeutisk eller kosmetisk användning. Köparen är 18 år eller äldre och bekräftar forskningssammanhanget. Inte ett läkemedel.