B7-33 6 mg

What is B7-33?

B7-33 is a synthetic peptide of 33 amino acids derived from the B-chain of human relaxin-2; the name refers to residues 7 to 33 of that chain. Whereas natural relaxin consists of two chains connected by disulfide bridges, B7-33 is a single-chain analog. This makes the compound significantly simpler and more stable to produce than the full hormone. Supplied as freeze-dried powder, 6 mg per sealed vial.

B7-33 binds to the RXFP1 receptor, the same receptor as relaxin-2, but with a different signal profile: the compound primarily activates the ERK pathway and the cAMP pathway much more weakly. This separate action makes B7-33 interesting in research as a tool to study the two signaling pathways of the same receptor independently.

What is B7-33 being investigated for?

Within controlled research environments, B7-33 is addressed in, among other things:

• Receptor binding: affinity and activation of the RXFP1 receptor.
• Signal selectivity: the preference for the CEFR route over the cAMP route, and what that distinction yields in cell models.
• Connective tissue models: collagen deposition and matrix turnover in cultured fibroblasts.
• Comparative study: the single-chain analog alongside complete relaxin-2.
• Peptide chemistry: stability and solubility of the single-chain structure relative to the two-chain hormone.
• Analytical reference: Calibration substance for peptide analysis via LC-MS.

It is important to emphasize that these applications take place exclusively within controlled research environments and that B7-33 is the subject of scientific research.

Buy B7-33 for research purposes

We supply B7-33 exclusively as a research chemical for professional laboratory research. The product is intended for:

• Scientific analysis
• Laboratory tests
• Research and Development (R&D)
• In vitro or analytical research

The material is supplied as freeze-dried powder in a sealed vial. View the stránka s výsledkami laboratórnych testov for our published test reports.

Important disclaimer – not for human or animal use

• Not intended for human use
• Not intended for animal use
• Not intended for diagnostic or therapeutic applications
• Not approved as a medicine or supplement

By purchasing, the buyer declares that the product is used exclusively for legitimate research purposes.

Why choose our B7-33?

• Rare in stock: a connection that is not available from most providers.
• Delivery within Europe: Shipping from the Netherlands, discreetly packaged and with track and trace.
• Transparent product information: Chain length, origin, and packaging are fully stated.
• Specifically for laboratory research: supplied and documented as a research chemical.

B7-33 is part of the Lumo research range and complements the other peptides we supply for matrix and repair-related laboratory research.