Dihexa 20mg (oral)

What is Dihexa?

Dihexa is an N-acylated oligopeptide derivative, structured around a dipeptide core of tyrosine and isoleucine (Tyr-Ile). The N-terminus is acylated with a hexanoyl group and the C-terminus is extended with a 6-aminohexanamide unit. The compound is also known in the literature by the development code PNB-0408 and bears the systematic name (2S,3S)-N-(6-amino-6-oxohexyl)-2-[[(2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanamide. The CAS number is 1401708-83-5, with PubChem CID 129010512, molecular formula C₂₇H₄₄N₄O₅ and a molecular weight of approximately 504.7 g/mol. Structurally, Dihexa is derived from the angiotensin IV motif and the compound is therefore classified as angiotensin IV derivative.

Pharmacologically, Dihexa is associated with the HGF/c-Met system in the literature: researchers describe the compound as a binding partner within this system and as a modulator of signal transduction via the receptor tyrosine kinase c-Met, with effects on receptor dimerization, autophosphorylation, and downstream kinase cascades in cell models. These properties make Dihexa a widely used model compound in research into N-acylated peptide analogs and growth factor signaling. Lumo supplies Dihexa as a tablet, exclusively for laboratory use.

What is Dihexa being investigated for?

Dihexa is used in preclinical and analytical research within multiple research directions. Examples described in the literature include:

• HGF/c-Met signaling — research into the interaction of the molecule with the receptor tyrosine kinase c-Met and the effects on receptor dimerization and autophosphorylation.
• Peptide-mediated signaling pathways — studies of downstream kinase cascades in cell models after exposure to the peptide.
• Investigação sobre a relação estrutura-atividade — comparative studies of N-acylated peptide analogs and the influence of acylation on receptor interaction.
• Lipophilia and membrane permeability — research into the influence of the hexanoyl group on the physicochemical properties of the molecule.
• Enzymatic stability — studies on the degradation resistance of N-acylated peptide derivatives.
• Analytical method development — use as a reference standard for HPLC and LC-MS methods.

It is important to emphasize that these applications take place exclusively within controlled research environments and that Dihexa is the subject of scientific research.

Buy Dihexa for research purposes

We supply Dihexa exclusively as a research chemical for professional laboratory research. The product is intended for:

• Análise científica
• Laboratory tests
• Research and Development (R&D)
• In vitro or analytical research

Dihexa is supplied in tablet form, pressed to a concentration of 20mg per tablet, with 25 tablets per package. Because tablets contain excipients, we use – as with our other tablet products – the concentration per unit (20mg) as the determining quality parameter instead of a purity percentage. Documentation regarding the delivered batch is available on our website. página de resultados laboratoriais.

Important disclaimer – not for human or animal use

Dihexa is sold exclusively for laboratory research. This product is:

• Não se destina a uso humano.
• Não se destina a uso em animais.
• Não se destina a aplicações de diagnóstico ou terapêuticas.
• Não aprovado como medicamento ou suplemento.

By purchasing, the buyer declares that the product is used exclusively for legitimate research purposes.

Why choose our Dihexa?

• Controlled content — each tablet contains a documented content of 20 mg Dihexa.
• Delivery within Europe — shipping from the Netherlands, discreetly packaged and with track & trace.
• Transparent product information — substance class, synonyms, CAS number, and molecular formula are listed with the product.
• Specifically for laboratory research — supplied in a form suitable for analytical and in vitro work.

Our focus is on supplying high-quality research chemicals to laboratories, research institutions, and R&D environments within neurobiological and biomedical research. Within that range, Dihexa is a highly sought-after reference compound for research into the HGF/c-Met system.