{"id":3001,"date":"2026-09-01T09:43:28","date_gmt":"2026-09-01T09:43:28","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=3001"},"modified":"2026-09-02T14:07:35","modified_gmt":"2026-09-02T14:07:35","slug":"aod-9604","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/sk\/product\/aod-9604\/","title":{"rendered":"AOD-9604"},"content":{"rendered":"<h2>What is AOD-9604?<\/h2>\n<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues with the sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe. The chain consists of the fifteen residues of a defined C-terminal fragment of a longer, naturally occurring polypeptide chain, supplemented by one additional tyrosine at the N-terminal position. The compound is known under CAS number 221231-10-3, with the molecular formula C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> (approximately 1815.1 g\/mol) and PubChem CID 71300630.<\/p>\n<p>The spatial structure is determined by the two cysteine \u200b\u200bresidues at positions 7 and 15, which form a disulfide bridge with each other. This bridge closes part of the sequence into a loop, giving the chain in solution a significantly more limited conformation range than a fully open chain of comparable length. The combination of a short, fully written-out sequence and exactly one internal bridge makes AOD-9604 a highly reproducible model compound in comparative peptide research: the closed and reduced forms differ by two mass units and can be separated chromatographically, making the substance useful in research into the formation, opening, and reoxidation of disulfide bridges.<\/p>\n<h2>Aplik\u00e1cie v laborat\u00f3rnom kontexte<\/h2>\n<p>Within peptide chemistry and analytical work, AOD-9604 occurs in the following in vitro research areas, among others:<\/p>\n<ul>\n<li><strong>V\u00fdskum vz\u0165ahu \u0161trukt\u00fary a aktivity<\/strong> to the contribution of the added N-terminal tyrosine and of both cysteine \u200b\u200bpositions to chain conformation, charge distribution, and chromatographic behavior.<\/li>\n<li><strong>V\u00fdskum peptidovej ch\u00e9mie<\/strong> towards solubility and aggregation tendency of short chains closed by a disulfide bridge in aqueous and mixed media.<\/li>\n<li><strong>\u0160t\u00fadie enzymatickej stability<\/strong> v ktorom sa rozpad re\u0165azca monitoruje za definovan\u00fdch podmienok pH, teploty a enz\u00fdmu a vytvoren\u00e9 fragmenty sa charakterizuj\u00fa hmotnostnou spektrometriou.<\/li>\n<li><strong>V\u00fdvoj a valid\u00e1cia analytick\u00fdch met\u00f3d<\/strong> (HPLC, LC-MS, peptide mapping) where the tyrosine residue provides a usable UV signal and the closed form serves as a reference peak alongside the reduced variant.<\/li>\n<\/ul>\n<h2>\u0160pecifik\u00e1cie<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Vzorka<\/strong><\/td>\n<td>AOD-9604 (synthetic peptide), freeze-dried in sealed vial<\/td>\n<\/tr>\n<tr>\n<td><strong>D\u013a\u017eka peptidu<\/strong><\/td>\n<td>16 amino acid residues<\/td>\n<\/tr>\n<tr>\n<td><strong>Postupnos\u0165<\/strong><\/td>\n<td>Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide bridge Cys7\u2013Cys15)<\/td>\n<\/tr>\n<tr>\n<td><strong>\u010c\u00edslo CAS<\/strong><\/td>\n<td>221231-10-3<\/td>\n<\/tr>\n<tr>\n<td><strong>Molekul\u00e1rny vzorec \/ hmotnos\u0165<\/strong><\/td>\n<td>C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> \/ approximately 1815.1 g\/mol<\/td>\n<\/tr>\n<tr>\n<td><strong>Trieda<\/strong><\/td>\n<td>Synthetic linear peptide with intramolecular disulfide bridge<\/td>\n<\/tr>\n<tr>\n<td><strong>Formul\u00e1r<\/strong><\/td>\n<td>Lyofilizovan\u00fd pr\u00e1\u0161ok (lyofilizovan\u00fd pr\u00e1\u0161ok) v uzavretej sklenenej liekovke<\/td>\n<\/tr>\n<tr>\n<td><strong>\u010cistota<\/strong><\/td>\n<td>\u2265 99 % (HPLC)<\/td>\n<\/tr>\n<tr>\n<td><strong>Skladovanie<\/strong><\/td>\n<td>Lyofilizovan\u00e9 pri teplote 2\u20138 \u00b0C, tmav\u00e9 a such\u00e9<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Tvar, manipul\u00e1cia a skladovanie<\/h2>\n<p>The material is supplied as freeze-dried powder (lyophilisate), white to off-white in color, in a sealed glass vial with a rubber septum and aluminum shrink cap. Short peptide lyophilisate is hygroscopic; therefore, the vial remains closed in the original packaging until the sample is taken into processing in the laboratory.<\/p>\n<p>Store the sealed vial freeze-dried at 2\u20138 \u00b0C, in a dark and dry place. The usual laboratory precautions apply: work in a clean, dry environment, avoid repeated temperature changes, and record the batch number and opening date for each vial in the lab logbook so that measurement series remain traceable afterwards. For chains containing a disulfide bridge, contact with reducing agents requires extra attention, as this alters the conformational profile of the sample.<\/p>\n<h2>Analytick\u00e1 kvalita<\/h2>\n<p>In comparative peptide analysis, the purity of the starting material determines how reliably the measurement results can be interpreted: shortened sequences and degradation products generate additional chromatographic peaks that may coincide with the main component. Our AOD-9604 is supplied with a purity of \u2265 99%, determined by HPLC analysis in accordance with the accompanying Certificate of Analysis. The available Certificates of Analysis can be viewed on our website. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">str\u00e1nka s v\u00fdsledkami laborat\u00f3rnych testov<\/a>.<\/p>\n<h2>D\u00f4le\u017eit\u00e9 vyhl\u00e1senie o vyl\u00fa\u010den\u00ed zodpovednosti<\/h2>\n<p>Tento produkt dod\u00e1vame v\u00fdhradne na laborat\u00f3rny v\u00fdskum a analytick\u00e9 pr\u00e1ce. Nie je ur\u010den\u00fd na diagnostick\u00e9 ani terapeutick\u00e9 aplik\u00e1cie a v\u00fdslovne nie je ur\u010den\u00fd na pou\u017eitie u \u013eud\u00ed alebo zvierat. Tento produkt nie je potravinou, doplnkom stravy, kozmetick\u00fdm v\u00fdrobkom ani registrovan\u00fdm liekom. K\u00fapou tohto produktu kupuj\u00faci potvrdzuje, \u017ee m\u00e1 18 rokov alebo viac a bude ho pou\u017e\u00edva\u0165 v\u00fdlu\u010dne v kontrolovanom v\u00fdskumnom alebo laborat\u00f3rnom prostred\u00ed.<\/p>","protected":false},"excerpt":{"rendered":"<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues (C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub>, approximately 1815.1 g\/mol) with an intramolecular disulfide bridge between the cysteine \u200b\u200bresidues at positions 7 and 15. Within scientific research, it is studied as a model compound in peptide chemistry and analytical work. Intended exclusively for laboratory and research purposes; not for human or animal use. Not a medicinal product.<\/p>","protected":false},"featured_media":3309,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[117,121],"product_tag":[],"class_list":["post-3001","product","type-product","status-publish","has-post-thumbnail","product_cat-metabool-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/3001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/comments?post=3001"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/3001\/revisions"}],"predecessor-version":[{"id":3061,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/3001\/revisions\/3061"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/media\/3309"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/media?parent=3001"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_brand?post=3001"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_cat?post=3001"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_tag?post=3001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}