Alkoholov\u00e9 utierky s\u00fa laborat\u00f3rny spotrebn\u00fd materi\u00e1l impregnovan\u00fd vodn\u00fdm roztokom 70 % izopropanolu, chemicky kr\u00e1tkeho, silne pol\u00e1rneho sekund\u00e1rneho alkoholu. Vo vedeckom v\u00fdskume sa izopropanol sk\u00fama ako modelov\u00e1 zl\u00fa\u010denina pre spr\u00e1vanie mal\u00fdch alkoholov na rozhraniach a pou\u017e\u00edva sa ako referen\u010dn\u00e1 kvapalina v analytick\u00fdch pr\u00e1cach. Tento produkt sa pon\u00faka ako 100 jednotlivo zataven\u00fdch utierok, v\u00fdhradne na laborat\u00f3rne a v\u00fdskumn\u00e9 \u00fa\u010dely.<\/p>\n
\u00da\u010dinnou zlo\u017ekou je prop\u00e1n-2-ol, molekula s tromi at\u00f3mami uhl\u00edka s hydroxylovou skupinou na centr\u00e1lnom at\u00f3me uhl\u00edka. V\u010faka kombin\u00e1cii mal\u00e9ho nepol\u00e1rneho uhl\u00edkov\u00e9ho chvosta a silne pol\u00e1rnej hydroxylovej skupiny je zl\u00fa\u010denina \u00faplne mie\u0161ate\u013en\u00e1 s vodou a z\u00e1rove\u0148 je schopn\u00e1 rozp\u00fa\u0161\u0165a\u0165 nepol\u00e1rne zvy\u0161ky. Tento amfifiln\u00fd charakter vysvet\u013euje, pre\u010do sa 70 % vodn\u00e1 zmes spr\u00e1va odli\u0161ne od \u010dist\u00e9ho alkoholu: voda zni\u017euje prchavos\u0165 a t\u00fdm predl\u017euje \u010das kontaktu na povrchu. Na kol\u00f3nach s reverznou f\u00e1zou vykazuje zl\u00fa\u010denina mal\u00fa retenciu a nesl\u00fa\u017ei ako analyt, ale ako siln\u00fd eluent a modifik\u00e1tor mobilnej f\u00e1zy.<\/p>\n
Vo v\u00fdskumn\u00fdch modeloch sa in vitro sk\u00fama mechanizmus p\u00f4sobenia alkoholov na prote\u00ednov\u00e9 a membr\u00e1nov\u00e9 \u0161trukt\u00fary. Izopropanol nar\u00fa\u0161a \u0161trukt\u00faru vod\u00edkov\u00fdch v\u00e4zieb okolo rozpusten\u00fdch prote\u00ednov, \u010do sp\u00f4sobuje rozvinutie terci\u00e1rnej \u0161trukt\u00fary a zni\u017euje usporiadanie lipidov\u00fdch dvojvrstiev v modelov\u00fdch membr\u00e1nach. Vodn\u00e1 zmes je v tomto oh\u013eade \u00fa\u010dinnej\u0161ia ako \u010dist\u00fd alkohol, preto\u017ee na preniknutie molekuly cez hydratovan\u00fa vonkaj\u0161iu vrstvu \u0161trukt\u00fary je potrebn\u00e1 voda. V d\u00f4sledku toho sa izopropanol pou\u017e\u00edva ako modelov\u00e1 zl\u00fa\u010denina a referen\u010dn\u00e1 l\u00e1tka vo vedeckom v\u00fdskume.<\/p>\n
V laborat\u00f3rnom kontexte sa alkoholov\u00e9 obr\u00fasky a \u00fa\u010dinn\u00e1 l\u00e1tka izopropanol pou\u017e\u00edvaj\u00fa okrem in\u00e9ho v nasleduj\u00facich oblastiach v\u00fdskumu:<\/p>\n
Ka\u017ed\u00e1 z t\u00fdchto aplik\u00e1ci\u00ed zah\u0155\u0148a kontrolovan\u00fd laborat\u00f3rny alebo predklinick\u00fd modelov\u00fd v\u00fdskum.<\/p>\n
Alcohol wipes fall under the category of laboratory consumables within our range: aids that support working with research compounds without being the subject of study themselves. While this item fulfills a physico-chemical function, namely dissolving and removing residues from a surface, other components within the same line have been selected to play a volumetric or mechanical role in the setup. They share the status of an aid but differ in composition and purpose.<\/p>\n
| \u0160pecifik\u00e1cia<\/th>\n | Hodnota<\/th>\n<\/tr>\n<\/thead>\n | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vzorka<\/td>\n | Alcohol wipes, 70% isopropanol<\/td>\n<\/tr>\n | ||||||||||||
| Synonym\u00e1<\/td>\n | propane-2-ol; 2-propanol; isopropyl alcohol; IPA<\/td>\n<\/tr>\n | ||||||||||||
| \u010c\u00edslo CAS<\/td>\n | 67-63-0 (isopropanol)<\/td>\n<\/tr>\n | ||||||||||||
| Molekul\u00e1rny vzorec \/ hmotnos\u0165<\/td>\n | C3<\/sub>H8<\/sub>O \/ 60.10 Da<\/td>\n<\/tr>\n| PubChem CID<\/td>\n | 3776<\/td>\n<\/tr>\n | Trieda<\/td>\n | Secondary aliphatic alcohol, polar and completely miscible with water<\/td>\n<\/tr>\n | Forma<\/td>\n | Pre-impregnated non-woven cloth in a sealed sachet<\/td>\n<\/tr>\n | Mno\u017estvo na jednotku<\/td>\n | 70% isopropanol in demineralized water (v\/v)<\/td>\n<\/tr>\n | Mno\u017estvo na balenie<\/td>\n | 100 wipes, individually sealed<\/td>\n<\/tr>\n | Skladovanie<\/td>\n | Store in a dry place at room temperature, protected from light and heat sources.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n | Tvar, manipul\u00e1cia a skladovanie<\/h2>\nEach wipe consists of a non-woven carrier saturated with the water-alcohol mixture and individually sealed in an aluminium-laminated sachet; this seal limits evaporation, so that the mixing ratio is maintained. The wipes are intended for single use: cleaning work surfaces, the outside of laboratory glassware, and the septa and closures of analysis vials. After use, the alcohol evaporates within a short time; no residual surface film is to be expected.<\/p>\n Store the packaging dry at room temperature, protected from direct light and away from heat sources and open flames; the mixture is flammable. Do not use a sachet with a damaged seal, as the mixing ratio is then no longer defined. Handle the wipes with the usual laboratory precautions: ventilated, clean environment, suitable personal protective equipment, no contact with eyes, and out of reach of unauthorized persons.<\/p>\n Zlo\u017eenie a laborat\u00f3rne v\u00fdsledky<\/h2>\nFor this article, the composition is expressed as the volume fraction of the active component, namely 70% isopropanol in demineralized water, rather than as a purity percentage of a solid.<\/p>\n |