{"id":2609,"date":"2026-09-01T09:15:03","date_gmt":"2026-09-01T09:15:03","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2609"},"modified":"2026-09-02T12:23:38","modified_gmt":"2026-09-02T12:23:38","slug":"mazdutide-10mg","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/sk\/product\/mazdutide-10mg\/","title":{"rendered":"Mazdutide 10mg"},"content":{"rendered":"<h2>\u010co je Mazdutid?<\/h2>\n<p>Mazdutid je syntetick\u00fd acylovan\u00fd polypeptid: dlh\u00fd re\u0165azec aminokysel\u00edn, ku ktor\u00e9mu je kovalentne pripojen\u00e1 mastn\u00e1 kyselina s dlh\u00fdm re\u0165azcom prostredn\u00edctvom linkeru na bo\u010dnom re\u0165azci lyz\u00ednov\u00e9ho zvy\u0161ku. Zl\u00fa\u010denina je zn\u00e1ma pod \u010d\u00edslom CAS 2259884-03-0 s molekulov\u00fdm vzorcom C<sub>210<\/sub>H<sub>322<\/sub>N<sub>46<\/sub>O<sub>67<\/sub> a molekulov\u00fa hmotnos\u0165 pribli\u017ene 4563 Da. To zara\u010fuje molekulu do lipopeptidov: peptidov\u00fdch re\u0165azcov, ktor\u00e9 nes\u00fa kovalentne viazan\u00fd chvost mastnej kyseliny.<\/p>\n<p>T\u00e1to acyl\u00e1cia je ur\u010duj\u00facim \u0161truktur\u00e1lnym znakom a drasticky men\u00ed fyzik\u00e1lno-chemick\u00fd profil re\u0165azca. Lipofiln\u00fd chvost pripojen\u00fd k inak preva\u017ene pol\u00e1rnemu re\u0165azcu men\u00ed rozpustnos\u0165 vo vodnom prostred\u00ed, zvy\u0161uje tendenciu k samoviazaniu a agreg\u00e1cii so zvy\u0161uj\u00facou sa koncentr\u00e1ciou a zvy\u0161uje nekovalentn\u00fa v\u00e4zbu na prote\u00edny in vitro. Preto\u017ee miesto v\u00e4zby na bo\u010dnom re\u0165azci lyz\u00ednu je chemicky definovan\u00e9, zl\u00fa\u010deninu mo\u017eno presne charakterizova\u0165; v\u010faka tomu je mazdutid u\u017eito\u010dnou modelovou zl\u00fa\u010deninou v porovn\u00e1vacom v\u00fdskume peptidov a v analytick\u00fdch sk\u00famaniach spr\u00e1vania dlh\u00fdch acylovan\u00fdch re\u0165azcov.<\/p>\n<h2>Aplik\u00e1cie v laborat\u00f3rnom kontexte<\/h2>\n<p>V r\u00e1mci peptidovej ch\u00e9mie a analytick\u00fdch pr\u00e1c sa mazdutid nach\u00e1dza okrem in\u00e9ho v nasleduj\u00facich oblastiach v\u00fdskumu in vitro:<\/p>\n<ul>\n<li><strong>V\u00fdskum vz\u0165ahu \u0161trukt\u00fary a aktivity<\/strong> k pr\u00edspevku jednotliv\u00fdch sekven\u010dn\u00fdch poz\u00edci\u00ed a acyla\u010dn\u00e9ho miesta k priestorov\u00e9mu pl\u00e1novaniu a rigidite re\u0165azca.<\/li>\n<li><strong>V\u00fdskum peptidovej ch\u00e9mie<\/strong> t\u00fdkaj\u00face sa rozpustnosti, amfifiln\u00e9ho spr\u00e1vania a agreg\u00e1cie acylovan\u00fdch re\u0165azcov vo vodnom a zmie\u0161anom prostred\u00ed a vplyvu pH a i\u00f3novej sily na to.<\/li>\n<li><strong>\u0160t\u00fadie enzymatickej stability<\/strong> v ktorom sa r\u00fdchlos\u0165 degrad\u00e1cie re\u0165azca in vitro porovn\u00e1va s r\u00fdchlos\u0165ou degrad\u00e1cie neacylovan\u00fdch anal\u00f3gov s cie\u013eom kvantifikova\u0165 pr\u00edspevok zvy\u0161ku mastnej kyseliny k stabilite re\u0165azca.<\/li>\n<li><strong>V\u00fdvoj a valid\u00e1cia analytick\u00fdch met\u00f3d<\/strong> (HPLC, LC-MS, mapovanie peptidov), kde materi\u00e1l sl\u00fa\u017ei ako referen\u010dn\u00fd \u0161tandard pre reten\u010dn\u00e9 spr\u00e1vanie, distrib\u00faciu n\u00e1boja a fragmentov\u00e9 vzory dlh\u00fdch acylovan\u00fdch peptidov.<\/li>\n<\/ul>\n<h2>\u0160pecifik\u00e1cie<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Vzorka<\/strong><\/td>\n<td>Mazdutid, 10 mg na injek\u010dn\u00fa liekovku<\/td>\n<\/tr>\n<tr>\n<td><strong>\u010c\u00edslo CAS<\/strong><\/td>\n<td>2259884-03-0<\/td>\n<\/tr>\n<tr>\n<td><strong>Molekul\u00e1rny vzorec \/ hmotnos\u0165<\/strong><\/td>\n<td>C<sub>210<\/sub>H<sub>322<\/sub>N<sub>46<\/sub>O<sub>67<\/sub> \u2014 pribli\u017ene 4563 Da<\/td>\n<\/tr>\n<tr>\n<td><strong>Trieda<\/strong><\/td>\n<td>Syntetick\u00fd acylovan\u00fd polypeptid (lipopeptid)<\/td>\n<\/tr>\n<tr>\n<td><strong>Formul\u00e1r<\/strong><\/td>\n<td>Lyofilizovan\u00fd pr\u00e1\u0161ok (lyofilizovan\u00fd pr\u00e1\u0161ok) v uzavretej sklenenej liekovke<\/td>\n<\/tr>\n<tr>\n<td><strong>\u010cistota<\/strong><\/td>\n<td>\u2265 99 % (HPLC)<\/td>\n<\/tr>\n<tr>\n<td><strong>Skladovanie<\/strong><\/td>\n<td>Lyofilizovan\u00e9 pri teplote 2\u20138 \u00b0C, tmav\u00e9 a such\u00e9<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Tvar, manipul\u00e1cia a skladovanie<\/h2>\n<p>Materi\u00e1l sa dod\u00e1va ako lyofilizovan\u00fd pr\u00e1\u0161ok (lyofiliz\u00e1t) v uzavretej sklenenej liekovke s gumenou priehradkou a hlin\u00edkov\u00fdm zmr\u0161\u0165ovac\u00edm uz\u00e1verom. Lyofilizovan\u00fd kol\u00e1\u010d je biely a\u017e sivobiely a jeho hustota sa m\u00f4\u017ee v jednotliv\u00fdch liekovk\u00e1ch l\u00ed\u0161i\u0165; t\u00e1to odch\u00fdlka je vlastn\u00e1 procesu lyofiliz\u00e1cie a ni\u010d nehovor\u00ed o kvalite materi\u00e1lu. Lyofiliz\u00e1ty acylovan\u00fdch peptidov s\u00fa hygroskopick\u00e9, a preto liekovka zost\u00e1va uzavret\u00e1 a v p\u00f4vodnom obale, k\u00fdm sa materi\u00e1l nespracuje v laborat\u00f3riu.<\/p>\n<p>Utesnen\u00fd lyofiliz\u00e1t skladujte pri teplote 2 \u2013 8 \u00b0C na tmavom a suchom mieste, chr\u00e1nenom pred svetlom, vlhkos\u0165ou a v\u00fdkyvmi teploty. Pred otvoren\u00edm nechajte chladen\u00fa injek\u010dn\u00fa liekovku zohria\u0165 na izbov\u00fa teplotu, aby ste zabr\u00e1nili tvorbe kondenz\u00e1cie na pr\u00e1\u0161ku. Okrem toho s materi\u00e1lom manipulujte pod\u013ea be\u017en\u00fdch laborat\u00f3rnych opatren\u00ed: pracujte v \u010distom prostred\u00ed, noste rukavice a ochranu o\u010d\u00ed a zvy\u0161n\u00fd materi\u00e1l zlikvidujte pod\u013ea platn\u00fdch pokynov.<\/p>\n<h2>Analytick\u00e1 kvalita<\/h2>\n<p>V pr\u00edpade dlh\u00e9ho acylovan\u00e9ho re\u0165azca ur\u010duje identita a \u010distota v\u00fdchodiskovej l\u00e1tky, ako interpretovate\u013en\u00e1 je s\u00e9ria meran\u00ed: dele\u010dn\u00e9 sekvencie a neacylovan\u00e9 varianty sa ve\u013emi podobaj\u00fa cie\u013eovej zl\u00fa\u010denine, no poskytuj\u00fa anom\u00e1lny analytick\u00fd sign\u00e1l. N\u00e1\u0161 Mazdutid sa dod\u00e1va s \u010distotou \u2265 99 %, stanovenou HPLC anal\u00fdzou v s\u00falade s prilo\u017een\u00fdm certifik\u00e1tom anal\u00fdzy. Dostupn\u00e9 certifik\u00e1ty anal\u00fdzy si m\u00f4\u017eete pozrie\u0165 na na\u0161ej webovej str\u00e1nke. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">str\u00e1nka s v\u00fdsledkami laborat\u00f3rnych testov<\/a>.<\/p>\n<h2>D\u00f4le\u017eit\u00e9 vyhl\u00e1senie o vyl\u00fa\u010den\u00ed zodpovednosti<\/h2>\n<p>Tento produkt dod\u00e1vame v\u00fdhradne na laborat\u00f3rny v\u00fdskum a analytick\u00e9 pr\u00e1ce. Nie je ur\u010den\u00fd na diagnostick\u00e9 ani terapeutick\u00e9 aplik\u00e1cie a v\u00fdslovne nie je ur\u010den\u00fd na pou\u017eitie u \u013eud\u00ed alebo zvierat. Tento produkt nie je potravinou, doplnkom stravy, kozmetick\u00fdm v\u00fdrobkom ani registrovan\u00fdm liekom. K\u00fapou tohto produktu kupuj\u00faci potvrdzuje, \u017ee m\u00e1 18 rokov alebo viac a bude ho pou\u017e\u00edva\u0165 v\u00fdlu\u010dne v kontrolovanom v\u00fdskumnom alebo laborat\u00f3rnom prostred\u00ed.<\/p>","protected":false},"excerpt":{"rendered":"<p>Mazdutid je syntetick\u00fd acylovan\u00fd polypeptid (C<sub>210<\/sub>H<sub>322<\/sub>N<sub>46<\/sub>O<sub>67<\/sub>, pribli\u017ene 4563 g\/mol), v ktorom je mastn\u00e1 kyselina s dlh\u00fdm re\u0165azcom kovalentne viazan\u00e1 na lyz\u00ednov\u00fd bo\u010dn\u00fd re\u0165azec prostredn\u00edctvom linkeru. V r\u00e1mci vedeck\u00e9ho v\u00fdskumu sa \u0161tuduje ako modelov\u00e1 zl\u00fa\u010denina v peptidovej ch\u00e9mii a analytick\u00fdch pr\u00e1cach. Ur\u010den\u00e9 v\u00fdlu\u010dne na laborat\u00f3rne a v\u00fdskumn\u00e9 \u00fa\u010dely; nie na pou\u017eitie u \u013eud\u00ed alebo zvierat. Nie je to liek.<\/p>","protected":false},"featured_media":3306,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[117,121],"product_tag":[],"class_list":["post-2609","product","type-product","status-publish","has-post-thumbnail","product_cat-metabool-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/2609","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/comments?post=2609"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/2609\/revisions"}],"predecessor-version":[{"id":2688,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/2609\/revisions\/2688"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/media\/3306"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/media?parent=2609"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_brand?post=2609"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_cat?post=2609"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_tag?post=2609"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}