{"id":2606,"date":"2026-09-01T09:14:40","date_gmt":"2026-09-01T09:14:40","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2606"},"modified":"2026-09-02T12:17:22","modified_gmt":"2026-09-02T12:17:22","slug":"cerebrolysin-60mg","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/sk\/product\/cerebrolysin-60mg\/","title":{"rendered":"Cerebrolyz\u00edn 60 mg"},"content":{"rendered":"<p>Cerebrolyz\u00edn je \u0161tandardizovan\u00fd neuropeptidov\u00fd pr\u00edpravok biologick\u00e9ho p\u00f4vodu, chemicky n\u00edzkomolekul\u00e1rna zmes peptidov\u00fdch fragmentov a vo\u013en\u00fdch aminokysel\u00edn. V r\u00e1mci vedeck\u00e9ho v\u00fdskumu sa \u0161tuduje ako modelov\u00e1 zl\u00fa\u010denina pre neurotrofick\u00fa signaliz\u00e1ciu a ako referen\u010dn\u00fd materi\u00e1l v analytick\u00fdch pr\u00e1cach. T\u00e1to zl\u00fa\u010denina sa pon\u00faka ako lyofiliz\u00e1t s hmotnos\u0165ou 60 mg na injek\u010dn\u00fa liekovku, v\u00fdhradne na laborat\u00f3rne a v\u00fdskumn\u00e9 \u00fa\u010dely.<\/p>\n<h2>\u010co je Cerebrolyz\u00edn?<\/h2>\n<p>Cerebrolyz\u00edn (v\u00fdvojov\u00fd k\u00f3d FPF-1070) nie je samostatn\u00e1 zl\u00fa\u010denina s jednou molekulovou \u0161trukt\u00farou, ale \u0161tandardizovan\u00e1 zmes, ktor\u00e1 vznik\u00e1 kontrolovan\u00fdm enzymatick\u00fdm \u0161tiepen\u00edm purifikovan\u00fdch prote\u00ednov z brav\u010dov\u00e9ho mozgov\u00e9ho tkaniva. V\u00fdsledkom je frakcia pozost\u00e1vaj\u00faca v\u00fdlu\u010dne z n\u00edzkomolekul\u00e1rnych zlo\u017eiek: peptidov\u00fdch fragmentov s hmotnos\u0165ou pod 10 kDa, spolu s v\u00fdznamn\u00fdm podielom vo\u013en\u00fdch aminokysel\u00edn. V publikovan\u00fdch analytick\u00fdch v\u00fdskumoch boli v tak\u00fdchto pr\u00edpravkoch rozl\u00ed\u0161en\u00e9 stovky jednotliv\u00fdch peptidov\u00fdch fragmentov. Pr\u00e1ve t\u00e1to zlo\u017een\u00e1, no reprodukovate\u013ene vyroben\u00e1 \u0161trukt\u00fara rob\u00ed z tejto zl\u00fa\u010deniny \u0161iroko pou\u017e\u00edvan\u00fd model pri \u0161t\u00fadiu komplexn\u00fdch peptidov\u00fdch zmes\u00ed a neurotrofick\u00fdch sign\u00e1lnych dr\u00e1h.<\/p>\n<p>Cerebrolyz\u00edn sa sk\u00fama vo v\u00fdskumn\u00fdch modeloch, preto\u017ee niektor\u00e9 z pr\u00edtomn\u00fdch fragmentov vykazuj\u00fa \u0161truktur\u00e1lnu podobnos\u0165 s akt\u00edvnymi dom\u00e9nami endog\u00e9nnych neurotrofick\u00fdch faktorov, vr\u00e1tane cili\u00e1rneho neurotrofick\u00e9ho faktora (CNTF), neurotrofick\u00e9ho faktora odvoden\u00e9ho z gliovej bunkovej l\u00ednie (GDNF) a inzul\u00ednu podobn\u00fdch rastov\u00fdch faktorov. In vitro boli tieto fragmenty op\u00edsan\u00e9 ako v\u00e4zbov\u00e9 na tyroz\u00ednkin\u00e1zov\u00e9 receptory neurotrof\u00ednov\u00e9ho syst\u00e9mu; v bunkov\u00fdch modeloch pozorovan\u00fd \u00fa\u010dinok mizne, ke\u010f je t\u00e1to receptorov\u00e1 dr\u00e1ha farmakologicky blokovan\u00e1, \u010do nazna\u010duje interakciu sprostredkovan\u00fa receptorom. Preto sa Cerebrolyz\u00edn pou\u017e\u00edva ako modelov\u00e1 zl\u00fa\u010denina a referen\u010dn\u00e1 l\u00e1tka vo vedeckom v\u00fdskume.<\/p>\n<h2>Oblasti v\u00fdskumu<\/h2>\n<p>V laborat\u00f3rnom kontexte sa Cerebrolysin pou\u017e\u00edva okrem in\u00e9ho v nasleduj\u00facich oblastiach v\u00fdskumu:<\/p>\n<ul>\n<li>V\u00fdskum neurotrofick\u00fdch sign\u00e1lnych dr\u00e1h a aktiv\u00e1cie tyroz\u00ednkin\u00e1zov\u00fdch receptorov sprostredkovanej receptormi v izolovan\u00fdch modeloch neuron\u00e1lnych buniek in vitro.<\/li>\n<li>Peptidov\u00fd chemick\u00fd a enzymologick\u00fd v\u00fdskum distrib\u00facie fragmentov, ktor\u00e9 vznikaj\u00fa kontrolovanou proteol\u00fdzou prote\u00ednov mozgov\u00e9ho tkaniva.<\/li>\n<li>\u0160t\u00fadie \u0161trukt\u00fary a aktivity kr\u00e1tkych peptidov\u00fdch fragmentov a ich afinity k receptorom neurotrof\u00ednov\u00e9ho syst\u00e9mu.<\/li>\n<li>Modelov\u00e9 \u0161t\u00fadie rastu neuritov, vetvenia dendritov a synaptickej plasticity v syst\u00e9moch neur\u00f3nov a bunkov\u00fdch kult\u00far.<\/li>\n<li>V\u00fdvoj a valid\u00e1cia analytick\u00fdch met\u00f3d (HPLC, charakteriz\u00e1cia peptidov) s pou\u017eit\u00edm Cerebrolyz\u00ednu ako referen\u010dn\u00e9ho materi\u00e1lu pre komplexn\u00e9 peptidov\u00e9 zmesi.<\/li>\n<li>\u0160t\u00fadie stability a rozpustnosti lyofilizovan\u00fdch peptidov\u00fdch zmes\u00ed za kontrolovan\u00fdch podmienok.<\/li>\n<\/ul>\n<p>Ka\u017ed\u00e1 z t\u00fdchto aplik\u00e1ci\u00ed zah\u0155\u0148a kontrolovan\u00fd laborat\u00f3rny alebo predklinick\u00fd modelov\u00fd v\u00fdskum.<\/p>\n<h2>Cerebrolyz\u00edn v na\u0161om v\u00fdskumnom sortimente<\/h2>\n<p>Cerebrolyz\u00edn patr\u00ed v r\u00e1mci n\u00e1\u0161ho produktov\u00e9ho radu do kateg\u00f3rie lyofilizovan\u00fdch zl\u00fa\u010den\u00edn vo forme liekoviek. V r\u00e1mci tohto radu zauj\u00edma \u0161peci\u00e1lne postavenie, preto\u017ee nejde o samostatn\u00fd peptid s pevnou aminokyselinovou sekvenciou, ale sk\u00f4r o \u0161tandardizovan\u00fa zmes. Zatia\u013e \u010do Cerebrolyz\u00edn sa sk\u00fama na \u00farovni signaliz\u00e1cie neurotrofick\u00fdch receptorov, in\u00e9 zlo\u017eky v r\u00e1mci tej istej produktovej rady boli \u0161peci\u00e1lne vybran\u00e9 na pokrytie enzymatick\u00fdch, hormon\u00e1lnych alebo \u0161trukt\u00farne s\u00favisiacich cie\u013eov. Tieto zl\u00fa\u010deniny maj\u00fa rovnak\u00fa lyofilizovan\u00fa formu liekoviek, ale z\u00e1sadne sa l\u00ed\u0161ia molekul\u00e1rnou triedou, p\u00f4vodom a sk\u00faman\u00fdm mechanizmom.<\/p>\n<h2>\u0160pecifik\u00e1cie<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u0160pecifik\u00e1cia<\/th>\n<th>Hodnota<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Vzorka<\/td>\n<td>Cerebrolyz\u00edn (zmes neuropeptidov)<\/td>\n<\/tr>\n<tr>\n<td>Synonym\u00e1<\/td>\n<td>Cerebrolyz\u00edn; FPF-1070; pr\u00edpravok neuropeptidu s n\u00edzkou molekulovou hmotnos\u0165ou<\/td>\n<\/tr>\n<tr>\n<td>\u010c\u00edslo CAS<\/td>\n<td>12656-61-0<\/td>\n<\/tr>\n<tr>\n<td>Trieda<\/td>\n<td>\u0160tandardizovan\u00e1 zmes peptidov s n\u00edzkou molekulovou hmotnos\u0165ou biologick\u00e9ho p\u00f4vodu (&lt; 10 kDa)<\/td>\n<\/tr>\n<tr>\n<td>Forma<\/td>\n<td>Lyofilizovan\u00fd pr\u00e1\u0161ok (lyofiliz\u00e1t) v injek\u010dnej liekovke<\/td>\n<\/tr>\n<tr>\n<td>Mno\u017estvo na injek\u010dn\u00fa liekovku<\/td>\n<td>60 mg<\/td>\n<\/tr>\n<tr>\n<td>Po\u010det liekoviek v balen\u00ed<\/td>\n<td>1<\/td>\n<\/tr>\n<tr>\n<td>Skladovanie<\/td>\n<td>Skladujte na chladnom a suchom mieste, chr\u00e1nenom pred svetlom a vlhkos\u0165ou.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Tvar, manipul\u00e1cia a skladovanie<\/h2>\n<p>Cerebrolyz\u00edn sa dod\u00e1va ako lyofilizovan\u00fd pr\u00e1\u0161ok so \u0161tandardizovan\u00fdm mno\u017estvom 60 mg na injek\u010dn\u00fa liekovku. Lyofiliz\u00e1t je such\u00e1, pevn\u00e1 l\u00e1tka; na rozdiel od pevn\u00fdch tabliet alebo kaps\u00fal je pre t\u00fato formu potrebn\u00e1 rekon\u0161tit\u00facia.<\/p>\n<p>Injek\u010dn\u00fa liekovku skladujte na chladnom a suchom mieste, chr\u00e1nenom pred priamym svetlom a vlhkos\u0165ou, v p\u00f4vodnom obale. So zl\u00fa\u010deninou manipulujte pod\u013ea \u0161tandardn\u00fdch laborat\u00f3rnych opatren\u00ed: pracujte v \u010distom prostred\u00ed, pou\u017e\u00edvajte vhodn\u00e9 osobn\u00e9 ochrann\u00e9 prostriedky a zabr\u00e1\u0148te kr\u00ed\u017eovej kontamin\u00e1cii s in\u00fdmi v\u00fdskumn\u00fdmi materi\u00e1lmi. Obal uchov\u00e1vajte mimo dosahu neopr\u00e1vnen\u00fdch os\u00f4b.<\/p>\n<h2>Zlo\u017eenie a laborat\u00f3rne v\u00fdsledky<\/h2>\n<p>Ke\u010f\u017ee Cerebrolysin pozost\u00e1va z mnoh\u00fdch jednotliv\u00fdch peptidov\u00fdch fragmentov a vo\u013en\u00fdch aminokysel\u00edn, obsah sa vyjadruje ako celkov\u00e9 mno\u017estvo \u0161tandardizovan\u00e9ho materi\u00e1lu na injek\u010dn\u00fa liekovku (60 mg) a nie ako percento \u010distoty jednej l\u00e1tky. Jednotliv\u00e9 \u010d\u00edslo \u010distoty HPLC nie je pre zmes tohto druhu v\u00fdpovedn\u00e9.<\/p>\n<p>Preh\u013ead dostupnej analytickej dokument\u00e1cie n\u00e1jdete na na\u0161ej <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">str\u00e1nka s v\u00fdsledkami laborat\u00f3rnych testov<\/a>Spr\u00e1vy sa tam zhroma\u017e\u010fuj\u00fa centr\u00e1lne, aby ste mohli \u00fadaje zahrn\u00fa\u0165 do vlastn\u00fdch v\u00fdskumn\u00fdch z\u00e1znamov.<\/p>\n<h2>\u010casto kladen\u00e9 ot\u00e1zky<\/h2>\n<p><strong>Do ktorej skupiny l\u00e1tok patr\u00ed Cerebrolysin?<\/strong><br \/>Cerebrolyz\u00edn nie je samostatn\u00fd peptid s pevnou aminokyselinovou sekvenciou, ale \u0161tandardizovan\u00e1 zmes n\u00edzkomolekul\u00e1rnych peptidov\u00fdch fragmentov (&lt; 10 kDa) a vo\u013en\u00e9 aminokyseliny z\u00edskan\u00e9 z enzymaticky \u0161tiepen\u00fdch prote\u00ednov brav\u010dov\u00e9ho mozgov\u00e9ho tkaniva.<\/p>\n<p><strong>\u010co sa rozumie pod neurotrofickou mimikryou vo v\u00fdskumnom kontexte?<\/strong><br \/>To znamen\u00e1, \u017ee niektor\u00e9 peptidov\u00e9 fragmenty v zmesi vykazuj\u00fa \u0161truktur\u00e1lnu podobnos\u0165 s akt\u00edvnymi dom\u00e9nami endog\u00e9nnych neurotrofick\u00fdch faktorov, ako s\u00fa CNTF a GDNF. In vitro sa tieto fragmenty via\u017eu na receptory neurotrof\u00ednov\u00e9ho syst\u00e9mu, v\u010faka \u010domu je t\u00e1to zmes \u00fastredn\u00fdm bodom v\u00fdskumu mechanistick\u00e9ho modelovania buniek.<\/p>\n<p><strong>V akej forme je dod\u00e1van\u00e1 zl\u00fa\u010denina?<\/strong><br \/>Ako lyofilizovan\u00fd pr\u00e1\u0161ok s hmotnos\u0165ou 60 mg v jednej injek\u010dnej liekovke. Pre t\u00fato formu je potrebn\u00e1 laborat\u00f3rna rekon\u0161tit\u00facia.<\/p>\n<p><strong>Ako m\u00e1m skladova\u0165 injek\u010dn\u00fa liekovku?<\/strong><br \/>Skladujte v chlade a suchu, chr\u00e1nen\u00e9 pred svetlom a vlhkos\u0165ou, najlep\u0161ie v p\u00f4vodnom obale.<\/p>","protected":false},"excerpt":{"rendered":"<p><strong>Cerebrolyz\u00edn \u2013 zmes neurotrofick\u00fdch peptidov pre v\u00fdskum kogn\u00edcie a neuroprotekcie<\/strong><br \/>Cerebrolyz\u00edn je \u0161tandardizovan\u00e1 zmes n\u00edzkomolekul\u00e1rnych neuropeptidov a vo\u013en\u00fdch aminokysel\u00edn, odvoden\u00e1 z purifikovan\u00e9ho brav\u010dov\u00e9ho mozgov\u00e9ho tkaniva. Jeho neurotrofick\u00e9 a neuroprotekt\u00edvne vlastnosti sa sk\u00famaj\u00fa v laborat\u00f3rnych a predklinick\u00fdch v\u00fdskumoch. Cerebrolyz\u00edn nie je spotrebite\u013esk\u00fd ani medic\u00ednsky produkt.<\/p>","protected":false},"featured_media":3252,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[122,121],"product_tag":[],"class_list":["post-2606","product","type-product","status-publish","has-post-thumbnail","product_cat-cognitief","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/2606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/comments?post=2606"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/2606\/revisions"}],"predecessor-version":[{"id":2686,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product\/2606\/revisions\/2686"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/media\/3252"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/media?parent=2606"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_brand?post=2606"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_cat?post=2606"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/sk\/wp-json\/wp\/v2\/product_tag?post=2606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}