AHK-Cu is a synthetic copper tripeptide complex composed of the amino acids alanine, histidine, and lysine (Ala-His-Lys), chelated with a divalent copper ion (Cu\u00b2\u207a). It belongs to the class of copper peptides and\u2014like the closely related GHK-Cu\u2014is studied in scientific research as a model compound in dermatological and biochemical laboratory systems. AHK-Cu is offered exclusively for laboratory and research purposes.<\/p>\n
AHK-Cu (systematically also referred to as Copper tripeptide-3) is a small tripeptide in which a single copper ion is firmly held by the peptide chain. The imidazole ring of the histidine residue and the nitrogen atoms of the peptide backbone together form a chelate environment that coordinates the Cu\u00b2\u207a ion. Thus, AHK-Cu is structurally related to the classical copper tripeptide GHK-Cu; the difference lies in the N-terminal residue, where AHK-Cu carries an alanine instead of the glycine of GHK-Cu.<\/p>\n
Due to this defined, reproducible structure, AHK-Cu serves in research as an accurate tool to study the chemistry of copper peptides and the dynamics of copper ions in model systems. Within the context of in vitro and preclinical research, the compound is used as a model compound, not as a means for human or animal application.<\/p>\n
In a controlled laboratory environment, AHK-Cu is used in the following research areas, among others:<\/p>\n
AHK-Cu is often compared to other copper peptides in research. The most studied related compound is GHK-CU<\/a>, the original copper tripeptide (Gly-His-Lys + Cu\u00b2\u207a) upon which much of the dermatological model literature is based. AHK-Cu and GHK-Cu share a similar chelation motif but differ in their N-terminal amino acid, which provides an interesting point of comparison in structure-activity models.<\/p>\n For research focusing on a topical, ready-to-use formulation, there are the serum variants. AHK-Cu Serum 30ml<\/a> \u015fi GHK-CU Serum 30ML<\/a>, in which the same active ingredients are incorporated into an aqueous research base. Those who wish to explore peptide chemistry surrounding skin and matrix models more broadly also often involve Matrixyl 10 mg<\/a> in the comparison, a matrix-targeted signal peptide that is studied in similar ECM models.<\/p>\nSpecifica\u021bii<\/h2>\n
| Specifica\u021bii<\/th>\n | Valoare<\/th>\n<\/tr>\n<\/thead>\n |
|---|---|
| E\u015fantion<\/td>\n | AHK-Cu (Alanyl-L-Histidyl-L-Lysine + copper(II) complex)<\/td>\n<\/tr>\n |
| Sinonime<\/td>\n | Copper tripeptide-3, AHK-Cu complex<\/td>\n<\/tr>\n |
| ID-ul PubChem<\/td>\n | 169450582<\/td>\n<\/tr>\n |
| Secven\u0163\u0103<\/td>\n | Ala-His-Lys (with Cu\u00b2\u207a)<\/td>\n<\/tr>\n |
| Clas\u0103<\/td>\n | Copper tripeptide complex<\/td>\n<\/tr>\n |
| Contents<\/td>\n | 100 mg<\/td>\n<\/tr>\n |
| Form\u0103<\/td>\n | Pulbere liofilizat\u0103 (pulbere uscat\u0103)<\/td>\n<\/tr>\n |
| Puritate<\/td>\n | \u2265 99% (HPLC)<\/td>\n<\/tr>\n |
| Depozitare<\/td>\n | A se p\u0103stra la frigider, ferit de lumin\u0103 \u0219i umiditate<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\nForm\u0103, manipulare \u0219i depozitare<\/h2>\nAHK-Cu is supplied as a freeze-dried powder (lyophilisate) in a 100 mg vial. The freeze-dried powder is stable when stored in a cool, dark place, protected from light and moisture. For use in a research setup, the compound is typically reconstituted with bacteriostatic water; after reconstitution, the solution is stored refrigerated (2\u20138 \u00b0C). When opening and dissolving, work in a clean, controlled environment and avoid repeated temperature fluctuations to maintain the integrity of the peptide-copper complex.<\/p>\n As a copper-containing complex, AHK-Cu has a characteristic blue to blue-purple color in solution; this color is inherent to the coordinated Cu\u00b2\u207a ion and is a normal feature of copper peptides.<\/p>\n Puritate \u0219i rezultate de laborator<\/h2>\nAHK-Cu is offered with a controlled purity of \u2265 99% (HPLC). Purity and identity are analytically determined by liquid chromatography. An overview of the available analysis certificates and lab results can be found on the pagina cu rezultate de laborator<\/a>.<\/p>\n What is the difference between AHK-Cu and GHK-Cu?<\/strong> In what form is AHK-Cu supplied?<\/strong> Why does AHK-Cu contain copper?<\/strong> How do I best store AHK-Cu?<\/strong> Is AHK-Cu suitable for human use?<\/strong> |