{"id":2582,"date":"2026-09-01T09:12:12","date_gmt":"2026-09-01T09:12:12","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2582"},"modified":"2026-09-02T12:21:04","modified_gmt":"2026-09-02T12:21:04","slug":"survodutide-10mg","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/ro\/product\/survodutide-10mg\/","title":{"rendered":"Survodutid\u0103 10 mg"},"content":{"rendered":"<p><strong>Numai pentru uz de laborator \u0219i cercetare. Nu este destinat uzului uman sau veterinar.<\/strong><\/p>\n<p>Survodutida este o peptid\u0103 sintetic\u0103, acilat\u0103, studiat\u0103 \u00een condi\u021bii de laborator controlate, \u00een cadrul c\u0103ilor de semnalizare mediate de peptide \u0219i al model\u0103rii interac\u021biunii receptorilor. \u00cen cercetarea \u0219tiin\u021bific\u0103, compusul este utilizat ca compus model \u0219i ca standard de referin\u021b\u0103 \u00een lucr\u0103rile analitice. Este oferit\u0103 sub form\u0103 de liofilizat liofilizat \u00eentr-un flacon experimental sigilat de 10 mg.<\/p>\n<h2>Ce este Survodutida?<\/h2>\n<p>Survodutida este o peptid\u0103 liniar\u0103 cu o mas\u0103 molecular\u0103 de aproximativ 4.232 Da, structurat\u0103 conform formulei moleculare C<sub>192<\/sub>H<sub>289<\/sub>N<sub>47<\/sub>O<sub>61<\/sub>Lan\u021bul este derivat dintr-o schelet peptidic natural \u0219i prezint\u0103 reziduuri de aminoacizi modificate \u00een mai multe pozi\u021bii. Un lan\u021b de acid gras C18 este ata\u0219at la un reziduu de lizin\u0103 printr-un linker hidrofil. Aceast\u0103 acilare modific\u0103 profilul fizico-chimic - hidrofobicitatea, comportamentul de agregare \u0219i afinitatea proteic\u0103 - f\u0103c\u00e2nd din compus un model util \u00een cercetarea modific\u0103rii lipidelor peptidelor sintetice.<\/p>\n<p>\u00cen modelele de cercetare, Survodutida este descris\u0103 ca un agonist dual al doi receptori cupla\u021bi cu proteina G de clasa B: receptorul GLP-1 \u0219i receptorul glucagonului. \u00cen modelele celulare in vitro, sunt examinate afinitatea de legare \u0219i transduc\u021bia semnalului intracelular, inclusiv r\u0103spunsul cAMP al sistemelor receptorilor exprima\u021bi. Datorit\u0103 profilului s\u0103u molecular definit, compusul serve\u0219te \u00een mod regulat ca input de referin\u021b\u0103 \u00een studiile comparative privind peptidele. \u00cen consecin\u021b\u0103, Survodutida este utilizat\u0103 ca compus model \u0219i substan\u021b\u0103 de referin\u021b\u0103 \u00een cercetarea \u0219tiin\u021bific\u0103.<\/p>\n<h2>Domenii de cercetare<\/h2>\n<p>\u00centr-un context de laborator, Survodutida este prezent\u0103 \u00een urm\u0103toarele domenii de cercetare, printre altele:<\/p>\n<ul>\n<li>Modelarea interac\u021biunii receptorilor cupla\u021bi cu proteine \u200b\u200bG de clasa B \u0219i caracterizarea afinit\u0103\u021bii de legare \u00een modelele celulare.<\/li>\n<li>Studii ale c\u0103ilor de semnalizare mediate de peptide \u0219i ale re\u021belelor de reglare molecular\u0103, inclusiv r\u0103spunsul cAMP in vitro.<\/li>\n<li>Studiul rela\u021biei structur\u0103-activitate privind contribu\u021bia reziduurilor de aminoacizi la selectivitatea liganzilor receptori duali.<\/li>\n<li>Cercet\u0103ri privind modificarea lipidelor \u0219i influen\u021ba unui lan\u021b de acizi gra\u0219i asupra conforma\u021biei, solubilit\u0103\u021bii \u0219i afinit\u0103\u021bii proteice.<\/li>\n<li>Dezvoltarea \u0219i validarea metodelor analitice (HPLC, LC-MS) utiliz\u00e2nd Survodutida ca standard de referin\u021b\u0103.<\/li>\n<li>Studiu comparativ \u00een cadrul clasei de peptide sintetice acilate \u00een condi\u021bii controlate.<\/li>\n<\/ul>\n<p>Fiecare dintre aceste aplica\u021bii implic\u0103 cercetare controlat\u0103 de laborator sau pe modele preclinice.<\/p>\n<h2>Specifica\u021bie analitic\u0103<\/h2>\n<p>The material is submitted with a controlled purity of \u2265 99%, determined via high-pressure liquid chromatography (HPLC). Identity and purity are determining parameters in analytical peptide work: in the case of a long, acylated chain, deletion sequences or degradation products can influence the interpretation of measurement results, especially when affinity values \u200b\u200bare derived from a concentration series. An overview of the available analysis documentation can be found on our <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">pagina cu rezultate de laborator<\/a>.<\/p>\n<h2>Specifica\u021bii<\/h2>\n<table>\n<thead>\n<tr>\n<th>Specifica\u021bii<\/th>\n<th>Valoare<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>E\u015fantion<\/td>\n<td>Survodutide<\/td>\n<\/tr>\n<tr>\n<td>Synonyms \/ development code<\/td>\n<td>BI 456906; BI-456906<\/td>\n<\/tr>\n<tr>\n<td>Num\u0103r CAS<\/td>\n<td>2805997-46-8<\/td>\n<\/tr>\n<tr>\n<td>Formula molecular\u0103 \/ greutate<\/td>\n<td>C<sub>192<\/sub>H<sub>289<\/sub>N<sub>47<\/sub>O<sub>61<\/sub> \/ \u00b1 4,231.7 Da<\/td>\n<\/tr>\n<tr>\n<td>ID-ul PubChem<\/td>\n<td>171378821<\/td>\n<\/tr>\n<tr>\n<td>Clas\u0103<\/td>\n<td>Acylated synthetic peptide; dual agonist of class B G-protein-coupled receptors<\/td>\n<\/tr>\n<tr>\n<td>Form\u0103<\/td>\n<td>Liofilizat liofilizat \u00een flacon sigilat<\/td>\n<\/tr>\n<tr>\n<td>Cantitate per flacon<\/td>\n<td>10 mg<\/td>\n<\/tr>\n<tr>\n<td>Puritate<\/td>\n<td>\u2265 99% (HPLC)<\/td>\n<\/tr>\n<tr>\n<td>Depozitare<\/td>\n<td>A se p\u0103stra \u00eentr-un loc r\u0103coros \u0219i \u00eentunecat, ferit de lumin\u0103 \u0219i umiditate.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Form\u0103, manipulare \u0219i depozitare<\/h2>\n<p>Survodutide is supplied as freeze-dried lyophilisate in a sealed 10 mg vial. The lyophilization process preserves the molecular integrity of the peptide chain during storage and transport. The material has a white to off-white appearance and presents as a loose powder or as a compressed cake; both are normal and relate to the conditions during freeze-drying. The lyophilisate is hygroscopic.<\/p>\n<p>Store the unopened lyophilized substance in a cool, dry, and dark place in the original packaging, protected from light and moisture. Allow a cooled vial to reach room temperature before opening to prevent condensation from forming on the glass. Observe the compound with standard laboratory precautions: work in a clean environment, use appropriate personal protective equipment, prevent cross-contamination, and keep the packaging out of reach of unauthorized persons. Dispose of residual material in accordance with applicable laboratory guidelines.<\/p>\n<h2>Survodutide within our research range<\/h2>\n<p>Within our product range, Survodutide falls under the category of freeze-dried investigational compounds in vial form. Researchers working with this category frequently combine the compound with other peptides that are studied via their own molecular target. While Survodutide distinguishes itself through an acylated chain with affinity for two receptors, other components within the same product line have been specifically chosen to cover enzymatic or metal-bound targets. These compounds share the vial form but differ in molecular class and investigated mechanism.<\/p>\n<h2>\u00centreb\u0103ri frecvente<\/h2>\n<p><strong>To which class of substances does Survodutide belong?<\/strong><br \/>Survodutide is a synthetic, acylated peptide described in the literature as a dual agonist of two class B G-protein-coupled receptors. It is known under the development code BI 456906.<\/p>\n<p><strong>Why is molecular structure relevant in research?<\/strong><br \/>The defined peptide chain with an attached C18 fatty acid chain gives the molecule a well-characterizable profile. This makes the compound useful as a model in receptor interaction research and as a reference in analytical methods.<\/p>\n<p><strong>Sub ce form\u0103 este furnizat compusul?<\/strong><br \/>Sub form\u0103 de liofilizat liofilizat \u00eentr-un flacon sigilat de 10 mg, cu o puritate \u2265 99% (HPLC).<\/p>\n<p><strong>Cum arat\u0103 materialul?<\/strong><br \/>White to off-white lyophilized material, as a loose powder or compressed cake. The material is hygroscopic and must be briefly exposed to ambient air.<\/p>\n<p><strong>Cum depozitez materialul?<\/strong><br \/>Store in a cool, dry, and dark place in the original packaging, protected from light and moisture.<\/p>","protected":false},"excerpt":{"rendered":"<p>Survodutida este o peptid\u0103 sintetic\u0103 experimental\u0103 din clasa agoni\u0219tilor duali ai receptorilor GLP-1\/glucagon, oferit\u0103 sub form\u0103 de liofilizat liofilizat. Destinat\u0103 exclusiv scopurilor de laborator \u0219i cercetare; nu este destinat\u0103 consumului uman sau animal. Nu este un produs medicinal sau supliment alimentar.<\/p>","protected":false},"featured_media":3289,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[117,121],"product_tag":[],"class_list":["post-2582","product","type-product","status-publish","has-post-thumbnail","product_cat-metabool-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/product\/2582","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/comments?post=2582"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/product\/2582\/revisions"}],"predecessor-version":[{"id":2662,"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/product\/2582\/revisions\/2662"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/media\/3289"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/media?parent=2582"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/product_brand?post=2582"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/product_cat?post=2582"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/ro\/wp-json\/wp\/v2\/product_tag?post=2582"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}