Fenbendazole is a synthetic small molecule belonging to the class of benzimidazole carbamates, chemically a 2-carbamate benzimidazole with a phenylthiosubstituent. In scientific research, it is studied as a model compound for tubulin interaction and oxidative biotransformation and as a reference standard in analytical work. This compound is offered as tablets containing 100 mg of active substance per tablet, exclusively for laboratory and research purposes.<\/p>\n
Fenbendazole (methyl-N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate) is a small organic molecule with the formula C15<\/sub>H13<\/sub>N3<\/sub>O2<\/sub>S and a molecular weight of 299.35 Da. The structure consists of three clearly distinguishable parts: the planar benzimidazole core, a methylcarbamate group at position 2, and a thioether connecting the core to a phenyl ring via a sulfur atom. This structure yields a strongly nonpolar molecule, barely soluble in water, with a high partition coefficient, while the benzimidazole nitrogen atom imparts a weakly acidic character. This combination makes Fenbendazole a widely used model compound in solubility research.<\/p>\n In research models, two mechanistic pathways are central. First, in vitro, the compound binds to beta-tubulin at the same site as colchicine, thereby delaying microtubule formation in cell-free polymerization assays; this makes it a useful tool in cytoskeleton and cell division research. Second, the disulfide bridge is the target of a two-stage oxidation: flavin-containing monooxygenases and cytochrome P450 enzymes first convert the thioether into the sulfoxide metabolite (oxfendazole) and subsequently into the corresponding sulfone. This sequential conversion makes the compound suitable for enzymatic and metabolic laboratory research. Consequently, Fenbendazole is used as a model compound and reference substance within scientific research.<\/p>\n In a laboratory context, Fenbendazole is found in the following research areas, among others:<\/p>\n Fiecare dintre aceste aplica\u021bii implic\u0103 cercetare controlat\u0103 de laborator sau pe modele preclinice.<\/p>\n Fenbendazole falls under the category of oral investigational compounds in solid tablet form within our product range. While this compound focuses on interaction with a cytoskeletal structural protein and on oxidative conversion, other components within the same product line have been specifically selected to cover receptor-linked or enzymatic targets, or to serve as peptide fragments. They share the solid tablet form but differ fundamentally in molecular class and investigated mechanism.<\/p>\n Fenbendazole is supplied as solid tablets with a standardized amount of 100 mg per tablet, packaged in units of 100. This solid form can be weighed directly in a laboratory setup. For analytical work, the very limited water solubility is the determining factor: separation methods typically work with an organic component in the mobile phase, and extraction from the tablet matrix requires an approach determined by the laboratory itself.<\/p>\n Store the tablets dry at room temperature, protected from direct light and moisture, in the original packaging. Handle the compound with the usual laboratory precautions: clean environment, suitable protective equipment, no cross-contamination. Keep the packaging out of reach of unauthorized persons.<\/p>\n For this compound, the content is expressed as the amount of active substance per tablet (100 mg per tablet) rather than as a purity percentage, as is customary for tablet and capsule formulations.<\/p>\nDomenii de cercetare<\/h2>\n
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Fenbendazole in our research assortment<\/h2>\n
Specifica\u021bii<\/h2>\n
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\n \nSpecifica\u021bii<\/th>\n Valoare<\/th>\n<\/tr>\n<\/thead>\n \n E\u015fantion<\/td>\n Fenbendazol<\/td>\n<\/tr>\n \n Sinonime<\/td>\n methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate; fenbendazole; fenbendazolum<\/td>\n<\/tr>\n \n Num\u0103r CAS<\/td>\n 43210-67-9<\/td>\n<\/tr>\n \n Formula molecular\u0103 \/ greutate<\/td>\n C15<\/sub>H13<\/sub>N3<\/sub>O2<\/sub>S \/ 299.35 Da<\/td>\n<\/tr>\n \n ID-ul PubChem<\/td>\n 3334<\/td>\n<\/tr>\n \n Clas\u0103<\/td>\n Small molecule, benzimidazole carbamate<\/td>\n<\/tr>\n \n Form\u0103<\/td>\n Tablets<\/td>\n<\/tr>\n \n Cantitate per unitate<\/td>\n 100 mg per tablet<\/td>\n<\/tr>\n \n Quantity per package<\/td>\n 100 tablets<\/td>\n<\/tr>\n \n Depozitare<\/td>\n Store in a dry place at room temperature, protected from light and moisture.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Form\u0103, manipulare \u0219i depozitare<\/h2>\n
Compozi\u021bie \u0219i rezultate de laborator<\/h2>\n