{"id":3001,"date":"2026-09-01T09:43:28","date_gmt":"2026-09-01T09:43:28","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=3001"},"modified":"2026-09-02T14:07:35","modified_gmt":"2026-09-02T14:07:35","slug":"aod-9604","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/pt\/product\/aod-9604\/","title":{"rendered":"AOD-9604"},"content":{"rendered":"<h2>What is AOD-9604?<\/h2>\n<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues with the sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe. The chain consists of the fifteen residues of a defined C-terminal fragment of a longer, naturally occurring polypeptide chain, supplemented by one additional tyrosine at the N-terminal position. The compound is known under CAS number 221231-10-3, with the molecular formula C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> (approximately 1815.1 g\/mol) and PubChem CID 71300630.<\/p>\n<p>The spatial structure is determined by the two cysteine \u200b\u200bresidues at positions 7 and 15, which form a disulfide bridge with each other. This bridge closes part of the sequence into a loop, giving the chain in solution a significantly more limited conformation range than a fully open chain of comparable length. The combination of a short, fully written-out sequence and exactly one internal bridge makes AOD-9604 a highly reproducible model compound in comparative peptide research: the closed and reduced forms differ by two mass units and can be separated chromatographically, making the substance useful in research into the formation, opening, and reoxidation of disulfide bridges.<\/p>\n<h2>Aplica\u00e7\u00f5es em contexto laboratorial<\/h2>\n<p>Within peptide chemistry and analytical work, AOD-9604 occurs in the following in vitro research areas, among others:<\/p>\n<ul>\n<li><strong>Investiga\u00e7\u00e3o sobre a rela\u00e7\u00e3o estrutura-atividade<\/strong> to the contribution of the added N-terminal tyrosine and of both cysteine \u200b\u200bpositions to chain conformation, charge distribution, and chromatographic behavior.<\/li>\n<li><strong>Investiga\u00e7\u00e3o em qu\u00edmica de pept\u00eddeos<\/strong> towards solubility and aggregation tendency of short chains closed by a disulfide bridge in aqueous and mixed media.<\/li>\n<li><strong>Estudos de estabilidade enzim\u00e1tica<\/strong> em que a quebra da cadeia \u00e9 monitorizada sob condi\u00e7\u00f5es definidas de pH, temperatura e enzima, e os fragmentos formados s\u00e3o caracterizados por espectrometria de massa.<\/li>\n<li><strong>Desenvolvimento e valida\u00e7\u00e3o de m\u00e9todos anal\u00edticos<\/strong> (HPLC, LC-MS, peptide mapping) where the tyrosine residue provides a usable UV signal and the closed form serves as a reference peak alongside the reduced variant.<\/li>\n<\/ul>\n<h2>Especifica\u00e7\u00f5es<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Amostra<\/strong><\/td>\n<td>AOD-9604 (synthetic peptide), freeze-dried in sealed vial<\/td>\n<\/tr>\n<tr>\n<td><strong>Comprimento do pept\u00eddeo<\/strong><\/td>\n<td>16 amino acid residues<\/td>\n<\/tr>\n<tr>\n<td><strong>Sequ\u00eancia<\/strong><\/td>\n<td>Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide bridge Cys7\u2013Cys15)<\/td>\n<\/tr>\n<tr>\n<td><strong>N\u00famero CAS<\/strong><\/td>\n<td>221231-10-3<\/td>\n<\/tr>\n<tr>\n<td><strong>F\u00f3rmula molecular \/ peso<\/strong><\/td>\n<td>C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> \/ approximately 1815.1 g\/mol<\/td>\n<\/tr>\n<tr>\n<td><strong>Aula<\/strong><\/td>\n<td>Synthetic linear peptide with intramolecular disulfide bridge<\/td>\n<\/tr>\n<tr>\n<td><strong>Forma<\/strong><\/td>\n<td>P\u00f3 liofilizado (p\u00f3 seco por congela\u00e7\u00e3o) em frasco de vidro selado.<\/td>\n<\/tr>\n<tr>\n<td><strong>Pureza<\/strong><\/td>\n<td>\u2265 99% (HPLC)<\/td>\n<\/tr>\n<tr>\n<td><strong>Armazenar<\/strong><\/td>\n<td>Liofilizado a 2\u20138 \u00b0C, escuro e seco<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Formato, manuseamento e armazenamento<\/h2>\n<p>The material is supplied as freeze-dried powder (lyophilisate), white to off-white in color, in a sealed glass vial with a rubber septum and aluminum shrink cap. Short peptide lyophilisate is hygroscopic; therefore, the vial remains closed in the original packaging until the sample is taken into processing in the laboratory.<\/p>\n<p>Store the sealed vial freeze-dried at 2\u20138 \u00b0C, in a dark and dry place. The usual laboratory precautions apply: work in a clean, dry environment, avoid repeated temperature changes, and record the batch number and opening date for each vial in the lab logbook so that measurement series remain traceable afterwards. For chains containing a disulfide bridge, contact with reducing agents requires extra attention, as this alters the conformational profile of the sample.<\/p>\n<h2>Qualidade anal\u00edtica<\/h2>\n<p>In comparative peptide analysis, the purity of the starting material determines how reliably the measurement results can be interpreted: shortened sequences and degradation products generate additional chromatographic peaks that may coincide with the main component. Our AOD-9604 is supplied with a purity of \u2265 99%, determined by HPLC analysis in accordance with the accompanying Certificate of Analysis. The available Certificates of Analysis can be viewed on our website. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">p\u00e1gina de resultados laboratoriais<\/a>.<\/p>\n<h2>Aviso importante<\/h2>\n<p>Fornecemos este produto estritamente para investiga\u00e7\u00e3o laboratorial e an\u00e1lises. N\u00e3o se destina a aplica\u00e7\u00f5es de diagn\u00f3stico ou terap\u00eauticas, e expressamente n\u00e3o para utiliza\u00e7\u00e3o em humanos ou animais. Este produto n\u00e3o \u00e9 um alimento, um suplemento, um produto cosm\u00e9tico ou um medicamento registado. Ao adquirir este produto, o comprador confirma que tem 18 anos de idade ou mais e que o utilizar\u00e1 exclusivamente num ambiente controlado de investiga\u00e7\u00e3o ou laborat\u00f3rio.<\/p>","protected":false},"excerpt":{"rendered":"<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues (C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub>, approximately 1815.1 g\/mol) with an intramolecular disulfide bridge between the cysteine \u200b\u200bresidues at positions 7 and 15. Within scientific research, it is studied as a model compound in peptide chemistry and analytical work. Intended exclusively for laboratory and research purposes; not for human or animal use. Not a medicinal product.<\/p>","protected":false},"featured_media":3309,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[117,121],"product_tag":[],"class_list":["post-3001","product","type-product","status-publish","has-post-thumbnail","product_cat-metabool-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product\/3001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/comments?post=3001"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product\/3001\/revisions"}],"predecessor-version":[{"id":3061,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product\/3001\/revisions\/3061"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/media\/3309"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/media?parent=3001"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product_brand?post=3001"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product_cat?post=3001"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product_tag?post=3001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}