{"id":2197,"date":"2026-09-01T08:43:07","date_gmt":"2026-09-01T08:43:07","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2197"},"modified":"2026-09-02T10:40:13","modified_gmt":"2026-09-02T10:40:13","slug":"cjc-1295-ipamorelin-pen","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/pt\/product\/cjc-1295-ipamorelin-pen\/","title":{"rendered":"CJC-1295 + Ipamorelin Pen"},"content":{"rendered":"<p>CJC-1295 without DAC and Ipamorelin are two synthetic peptides that each act on a specific receptor of the pituitary axis in research models. Within scientific research, they are studied together as a model pair for the interaction between two release pathways and as a reference standard in analytical work. This combination is offered as a 3 ml pre-filled injection pen containing 5 mg of each peptide, exclusively for laboratory and research purposes.<\/p>\n<h2>What is inside this pen?<\/h2>\n<p>The cartridge contains both peptides in a fixed 1:1 ratio, pre-combined in a single solution. CJC-1295 without DAC, also known in the literature as Mod GRF(1-29), is a modified fragment of 29 amino acids of the growth hormone-releasing hormone. Four amino acid substitutions at positions 2, 8, 15, and 27 make the chain more resistant to enzymatic degradation than the unmodified GRF(1-29); binding to the GHRH receptor is studied in research models.<\/p>\n<p>Ipamorelin is a selective pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH<sub>2<\/sub> which acts on the growth hormone secretagogue receptor, also known as the ghrelin receptor. The two D-amino acids and the non-proteinogenic Aib at the start of the chain make the compound insensitive to the usual degradation pathways and provide a pronounced selectivity profile with respect to related secretagogues. Because both molecules act via a different receptor, pairing is considered in the literature as a classic model for studying the interplay between two signaling pathways.<\/p>\n<h2>\u00c1reas de investiga\u00e7\u00e3o<\/h2>\n<p>In a laboratory context, this combination occurs in the following research areas, among others:<\/p>\n<ul>\n<li>Receptor pharmacology \u2014 binding studies to the GHRH receptor and the growth hormone secretagogue receptor in cell models.<\/li>\n<li>Signal transduction \u2014 measurement of second messenger systems with simultaneous activation of both routes.<\/li>\n<li>Selectivity study \u2014 comparison with related secretagogues to determine the receptor specificity of the pentapeptide.<\/li>\n<li>Structure-activity research \u2014 the role of D-amino acids and Aib in the resistance of short chains to peptidases.<\/li>\n<li>Analytical method development \u2014 separation of two peptides from a single solution using RP-HPLC and LC-MS.<\/li>\n<li>Stability study \u2014 behavior of a two-component solution at varying pH, ionic strength, and storage temperature.<\/li>\n<\/ul>\n<p>Cada uma destas aplica\u00e7\u00f5es envolve investiga\u00e7\u00e3o controlada em laborat\u00f3rio ou em modelos pr\u00e9-cl\u00ednicos.<\/p>\n<h2>CJC-1295 + Ipamorelin in our research assortment<\/h2>\n<p>This version belongs to the line of pre-filled injection pens: compounds contained in dissolved form in a sealed cartridge, so that a researcher does not need to go through their own dissolution step. The same combination is available elsewhere in the range as freeze-dried lyophilisate in a vial, and both peptides are also available separately. Other compounds within the pen line act on an entirely different biochemical system; the form indicates nothing about the substance class.<\/p>\n<h2>Especifica\u00e7\u00f5es<\/h2>\n<table>\n<thead>\n<tr>\n<th>Especifica\u00e7\u00e3o<\/th>\n<th>Valor<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Amostra<\/td>\n<td>CJC-1295 without DAC (Mod GRF 1-29) + Ipamorelin<\/td>\n<\/tr>\n<tr>\n<td>Sin\u00f4nimos<\/td>\n<td>Modified GRF (1-29); tetra-substituted GRF(1-29) Ipamorelin: NNC 26-0161<\/td>\n<\/tr>\n<tr>\n<td>Sequ\u00eancia<\/td>\n<td>Ipamorelin: Aib-His-D-2-Nal-D-Phe-Lys-NH<sub>2<\/sub> \u00b7 CJC-1295: modified GRF fragment of 29 amino acids<\/td>\n<\/tr>\n<tr>\n<td>N\u00famero CAS<\/td>\n<td>170851-70-4 (Ipamorelin)<\/td>\n<\/tr>\n<tr>\n<td>F\u00f3rmula molecular \/ peso<\/td>\n<td>C<sub>152<\/sub>H<sub>252<\/sub>N<sub>44<\/sub>O<sub>42<\/sub> \/ \u00b1 3367.9 Da \u00b7 C<sub>38<\/sub>H<sub>49<\/sub>N<sub>9<\/sub>O<sub>5<\/sub> \/ 711,9 Da<\/td>\n<\/tr>\n<tr>\n<td>PubChem CID<\/td>\n<td>9831659 (Ipamorelin)<\/td>\n<\/tr>\n<tr>\n<td>Aula<\/td>\n<td>GHRH analog + selective pentapeptide, 1:1 combination<\/td>\n<\/tr>\n<tr>\n<td>Forma<\/td>\n<td>Pre-filled injection pen with sealed cartridge<\/td>\n<\/tr>\n<tr>\n<td>Quantidade por unidade<\/td>\n<td>5 mg + 5 mg per 3 ml pen<\/td>\n<\/tr>\n<tr>\n<td>Quantity per package<\/td>\n<td>1 pen, 10 pen needles and alcohol wipes<\/td>\n<\/tr>\n<tr>\n<td>Armazenar<\/td>\n<td>Refrigerated at 2\u20138 \u00b0C, store in a dark place.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Formato, manuseamento e armazenamento<\/h2>\n<p>Both peptides are dissolved in a sealed 3 ml glass cartridge in a pen with a click mechanism. A separate dissolution step is not required with this version; the cartridge remains closed until a needle is inserted. The label includes a table showing the relationship between click settings and dispensed volume, allowing sample collections to be reproducibly recorded in a protocol.<\/p>\n<p>Store the pen refrigerated between 2 and 8 \u00b0C, protected from light and in the original packaging. Handle the pen in a clean working environment, use a new sterile needle for each draw to prevent cross-contamination, and wear standard personal protective equipment. Keep the material out of reach of unauthorized persons.<\/p>\n<h2>Composi\u00e7\u00e3o e resultados laboratoriais<\/h2>\n<p>Both raw materials have a controlled purity of \u2265 99% (HPLC). The pen contains the two peptides in a sterile aqueous base in a 1:1 ratio; the total amount per component is stated on the label.<\/p>\n<p>Analysis certificates of the relevant parties are on our <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">p\u00e1gina de resultados laboratoriais<\/a>.<\/p>\n<h2>Perguntas frequentes<\/h2>\n<p><strong>To which class of substances do these two compounds belong?<\/strong><br \/>CJC-1295 without DAC is a modified peptide fragment of 29 amino acids, derived from growth hormone-releasing hormone. Ipamorelin is a synthetic pentapeptide with two D-amino acids and an Aib residue at the start of the chain.<\/p>\n<p><strong>O que significa \u201csem DAC\u201d?<\/strong><br \/>DAC stands for Drug Affinity Complex, a chemical additive that extends the chain circulation time in models. In the variant without DAC, this additive is absent, making the profile closer to that of the unprocessed GRF(1-29) fragment.<\/p>\n<p><strong>In what form is the combination delivered?<\/strong><br \/>As a pre-filled injection pen with a sealed 3 ml cartridge containing 5 mg of both peptides. The box also contains ten sterile pen needles and alcohol wipes.<\/p>\n<p><strong>How do I store the pen?<\/strong><br \/>Refrigerated between 2 and 8 \u00b0C, in a dark place and in the original packaging. Do not freeze.<\/p>","protected":false},"excerpt":{"rendered":"<p>3 ml pre-filled injection pen containing 5 mg CJC-1295 without DAC and 5 mg Ipamorelin, supplied with 10 sterile pen needles and 10 alcohol wipes. For research purposes only.<\/p>","protected":false},"featured_media":3156,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[126],"product_tag":[],"class_list":["post-2197","product","type-product","status-publish","has-post-thumbnail","product_cat-pennen","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product\/2197","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/comments?post=2197"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product\/2197\/revisions"}],"predecessor-version":[{"id":2270,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product\/2197\/revisions\/2270"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/media\/3156"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/media?parent=2197"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product_brand?post=2197"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product_cat?post=2197"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/pt\/wp-json\/wp\/v2\/product_tag?post=2197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}