Tesofensina 500mcg

What is Tesofensine?

Tesofensine is a small synthetic molecule belonging to the class of phenyltropanes. The compound is known by CAS number 195875-84-4 with the molecular formula C₁₇H₂₃Cl₂NO and is systematically described as (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane. The skeleton is an 8-azabicyclo[3.2.1]octane framework with a methyl group on the bridge nitrogen atom, which bears a 3,4-dichlorophenyl group at position 3 and an ethoxymethyl side chain at position 2.

Two characteristics define the analytical profile of the molecule: the fully fixed configuration over four chiral centers and the conformationally highly restricted bicyclic skeleton. Both make the compound clearly distinguishable from the corresponding stereoisomers and from structure-related phenyltropanes, which makes Tesofensine a highly characterizable reference substance in chromatographic separation work and comparative structural analysis. This article concerns a solid unit form with a content of 500 µg per unit.

Aplicações em contexto laboratorial

In analytical chemistry, Tesofensine occurs as a reference substance in the following laboratory applications, among others:

• Determination of content and uniformity of content where the content per unit is determined chromatographically and the dispersion thereof over a series of individual units is statistically assessed.
• Identity verification where the retention time, UV spectrum, and mass spectrometric fragmentation pattern of a sample are compared with those of a characterized reference sample.
• Chromatographic purity determination and related substances analysis to synthesis residues, degradation products and stereoisomeric admixtures, which for this class of substances only become reliably visible with a separate peak system.
• Method development and validation (HPLC, LC-MS) in which the linearity, accuracy, repeatability, and detection limit of a measurement method on a reference substance of known composition are determined.

Especificações

Formato, manuseamento e armazenamento

Tesofensine is supplied as solid, individually handleable units in a sealed research package. This solid form maintains the molecular integrity of the material during storage and transport and makes the sample immediately ready for analytical work without intermediate processing. The material is sensitive to moisture and light and therefore remains in the closed original packaging until the moment of analysis.

Store the material in a cool, dry, and dark place and observe standard laboratory precautions: work in a clean environment, use appropriate personal protective equipment, prevent cross-contamination with other research materials, and keep the packaging out of reach of unauthorized persons. Residual material is disposed of in accordance with applicable laboratory guidelines.

Qualidade analítica

Identity and composition are determining parameters in analytical work with small molecules: impurities, degradation products, or stereoisomeric admixtures shift the calculated values ​​in a measurement series and, consequently, the interpretation of the results. Our Tesofensine is supplied with a content per unit determined by HPLC analysis, documented in the accompanying certificate of analysis. The available certificates of analysis can be viewed on our website. página de resultados laboratoriais.

Aviso importante

Fornecemos este produto estritamente para investigação laboratorial e análises. Não se destina a aplicações de diagnóstico ou terapêuticas, e expressamente não para utilização em humanos ou animais. Este produto não é um alimento, um suplemento, um produto cosmético ou um medicamento registado. Ao adquirir este produto, o comprador confirma que tem 18 anos de idade ou mais e que o utilizará exclusivamente num ambiente controlado de investigação ou laboratório.