{"id":3001,"date":"2026-09-01T09:43:28","date_gmt":"2026-09-01T09:43:28","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=3001"},"modified":"2026-09-02T14:07:35","modified_gmt":"2026-09-02T14:07:35","slug":"aod-9604","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/pl\/product\/aod-9604\/","title":{"rendered":"AOD-9604"},"content":{"rendered":"<h2>What is AOD-9604?<\/h2>\n<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues with the sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe. The chain consists of the fifteen residues of a defined C-terminal fragment of a longer, naturally occurring polypeptide chain, supplemented by one additional tyrosine at the N-terminal position. The compound is known under CAS number 221231-10-3, with the molecular formula C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> (approximately 1815.1 g\/mol) and PubChem CID 71300630.<\/p>\n<p>The spatial structure is determined by the two cysteine \u200b\u200bresidues at positions 7 and 15, which form a disulfide bridge with each other. This bridge closes part of the sequence into a loop, giving the chain in solution a significantly more limited conformation range than a fully open chain of comparable length. The combination of a short, fully written-out sequence and exactly one internal bridge makes AOD-9604 a highly reproducible model compound in comparative peptide research: the closed and reduced forms differ by two mass units and can be separated chromatographically, making the substance useful in research into the formation, opening, and reoxidation of disulfide bridges.<\/p>\n<h2>Zastosowania w kontek\u015bcie laboratoryjnym<\/h2>\n<p>Within peptide chemistry and analytical work, AOD-9604 occurs in the following in vitro research areas, among others:<\/p>\n<ul>\n<li><strong>Badania zale\u017cno\u015bci struktura-aktywno\u015b\u0107<\/strong> to the contribution of the added N-terminal tyrosine and of both cysteine \u200b\u200bpositions to chain conformation, charge distribution, and chromatographic behavior.<\/li>\n<li><strong>Badania chemii peptyd\u00f3w<\/strong> towards solubility and aggregation tendency of short chains closed by a disulfide bridge in aqueous and mixed media.<\/li>\n<li><strong>Badania stabilno\u015bci enzymatycznej<\/strong> w kt\u00f3rym rozk\u0142ad \u0142a\u0144cucha jest monitorowany w okre\u015blonych warunkach pH, \u200b\u200btemperatury i enzym\u00f3w, a powsta\u0142e fragmenty s\u0105 charakteryzowane za pomoc\u0105 spektrometrii masowej.<\/li>\n<li><strong>Opracowywanie i walidacja metod analitycznych<\/strong> (HPLC, LC-MS, peptide mapping) where the tyrosine residue provides a usable UV signal and the closed form serves as a reference peak alongside the reduced variant.<\/li>\n<\/ul>\n<h2>Specyfikacje<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Pr\u00f3bka<\/strong><\/td>\n<td>AOD-9604 (synthetic peptide), freeze-dried in sealed vial<\/td>\n<\/tr>\n<tr>\n<td><strong>D\u0142ugo\u015b\u0107 peptydu<\/strong><\/td>\n<td>16 amino acid residues<\/td>\n<\/tr>\n<tr>\n<td><strong>Sekwencja<\/strong><\/td>\n<td>Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide bridge Cys7\u2013Cys15)<\/td>\n<\/tr>\n<tr>\n<td><strong>Numer CAS<\/strong><\/td>\n<td>221231-10-3<\/td>\n<\/tr>\n<tr>\n<td><strong>Wz\u00f3r cz\u0105steczkowy \/ masa<\/strong><\/td>\n<td>C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> \/ approximately 1815.1 g\/mol<\/td>\n<\/tr>\n<tr>\n<td><strong>Klasa<\/strong><\/td>\n<td>Synthetic linear peptide with intramolecular disulfide bridge<\/td>\n<\/tr>\n<tr>\n<td><strong>Formularz<\/strong><\/td>\n<td>Liofilizowany proszek (liofilizowany proszek) w szczelnie zamkni\u0119tej szklanej fiolce<\/td>\n<\/tr>\n<tr>\n<td><strong>Czysto\u015b\u0107<\/strong><\/td>\n<td>\u2265 99% (HPLC)<\/td>\n<\/tr>\n<tr>\n<td><strong>Sk\u0142adowanie<\/strong><\/td>\n<td>Suszone liofilizowane w temperaturze 2\u20138 \u00b0C, ciemne i suche<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Kszta\u0142t, obs\u0142uga i przechowywanie<\/h2>\n<p>The material is supplied as freeze-dried powder (lyophilisate), white to off-white in color, in a sealed glass vial with a rubber septum and aluminum shrink cap. Short peptide lyophilisate is hygroscopic; therefore, the vial remains closed in the original packaging until the sample is taken into processing in the laboratory.<\/p>\n<p>Store the sealed vial freeze-dried at 2\u20138 \u00b0C, in a dark and dry place. The usual laboratory precautions apply: work in a clean, dry environment, avoid repeated temperature changes, and record the batch number and opening date for each vial in the lab logbook so that measurement series remain traceable afterwards. For chains containing a disulfide bridge, contact with reducing agents requires extra attention, as this alters the conformational profile of the sample.<\/p>\n<h2>Jako\u015b\u0107 analityczna<\/h2>\n<p>In comparative peptide analysis, the purity of the starting material determines how reliably the measurement results can be interpreted: shortened sequences and degradation products generate additional chromatographic peaks that may coincide with the main component. Our AOD-9604 is supplied with a purity of \u2265 99%, determined by HPLC analysis in accordance with the accompanying Certificate of Analysis. The available Certificates of Analysis can be viewed on our website. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">strona z wynikami bada\u0144 laboratoryjnych<\/a>.<\/p>\n<h2>Wa\u017cne zastrze\u017cenie<\/h2>\n<p>Dostarczamy ten produkt wy\u0142\u0105cznie do bada\u0144 laboratoryjnych i prac analitycznych. Nie jest on przeznaczony do zastosowa\u0144 diagnostycznych ani terapeutycznych i wyra\u017anie nie jest przeznaczony do stosowania u ludzi ani zwierz\u0105t. Produkt nie jest \u017cywno\u015bci\u0105, suplementem diety, produktem kosmetycznym ani zarejestrowanym produktem leczniczym. Kupuj\u0105c ten produkt, nabywca potwierdza, \u017ce \u200b\u200bma uko\u0144czone 18 lat i b\u0119dzie go u\u017cywa\u0142 wy\u0142\u0105cznie w kontrolowanym \u015brodowisku badawczym lub laboratoryjnym.<\/p>","protected":false},"excerpt":{"rendered":"<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues (C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub>, approximately 1815.1 g\/mol) with an intramolecular disulfide bridge between the cysteine \u200b\u200bresidues at positions 7 and 15. Within scientific research, it is studied as a model compound in peptide chemistry and analytical work. Intended exclusively for laboratory and research purposes; not for human or animal use. Not a medicinal product.<\/p>","protected":false},"featured_media":3309,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[117,121],"product_tag":[],"class_list":["post-3001","product","type-product","status-publish","has-post-thumbnail","product_cat-metabool-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/product\/3001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/comments?post=3001"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/product\/3001\/revisions"}],"predecessor-version":[{"id":3061,"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/product\/3001\/revisions\/3061"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/media\/3309"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/media?parent=3001"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/product_brand?post=3001"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/product_cat?post=3001"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/pl\/wp-json\/wp\/v2\/product_tag?post=3001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}