GHK-Cu is a naturally occurring metallopeptide, chemically a coordination complex of the tripeptide glycyl-L-histidyl-L-lysine with a copper(II) ion. In scientific research, it is studied as a model compound for metal-peptide coordination chemistry and as a reference standard in analytical work. This compound is offered as a 3 ml pre-filled injection pen, exclusively for laboratory and research purposes.<\/p>\n
GHK-Cu (glycyl-L-histidyl-L-lysine-copper(II), also referred to in the literature as copper tripeptide-1 or prezatide-copper) consists of a short chain of glycine, histidine, and lysine that jointly coordinate a single copper(II) ion. The metal ion is fixed via the imidazole ring of histidine, the terminal amino group of glycine, and the intervening peptide bond. This defined geometry makes the compound reproducible and thus useful as a model in the coordination chemistry of short peptides.<\/p>\n
In research models, the complex functions as an exchangeable reservoir for copper(II): the peptide portion holds the metal ion in a fixed coordination, allowing transfer to copper-binding proteins and enzymes to be quantitatively monitored in vitro. In addition, the influence on gene expression around the extracellular matrix is \u200b\u200bstudied in cell models. Consequently, GHK-Cu is used as a model compound and reference substance within scientific research.<\/p>\n
In ambito di laboratorio, il GHK-Cu trova applicazione, tra gli altri, nei seguenti settori di ricerca:<\/p>\n
Ciascuna di queste applicazioni prevede ricerche controllate in laboratorio o su modelli preclinici.<\/p>\n
This version belongs to the line of pre-filled injection pens: compounds contained in dissolved form in a sealed cartridge, so that a researcher does not need to go through their own dissolution step. The same compound is available elsewhere in the range as freeze-dried lyophilisate in a vial, as a kit, and in an aqueous base for topical modeling. Other compounds within the pen line act on a completely different biochemical system; the form indicates nothing about the substance class.<\/p>\n
| Specifiche<\/th>\n | Valore<\/th>\n<\/tr>\n<\/thead>\n | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Campione<\/td>\n | GHK-Cu<\/td>\n<\/tr>\n | ||||||||||||
| Siciliano<\/td>\n | Glycyl-L-histidyl-L-lysine-copper(II); copper tripeptide-1; prezatide copper<\/td>\n<\/tr>\n | ||||||||||||
| Numero CAS<\/td>\n | 89030-95-5 (copper complex); 49557-75-7 (free tripeptide)<\/td>\n<\/tr>\n | ||||||||||||
| Formula molecolare \/ peso<\/td>\n | C14<\/sub>H23<\/sub>CuN6<\/sub>O4<\/sub> (cation) \/ 402.92 Da<\/td>\n<\/tr>\n| PubChem CID<\/td>\n | 71587328 (copper complex); 73587 (free tripeptide)<\/td>\n<\/tr>\n | Classe<\/td>\n | Tripeptide-copper(II) complex (metallopeptide)<\/td>\n<\/tr>\n | Modulo<\/td>\n | Pre-filled injection pen with sealed cartridge<\/td>\n<\/tr>\n | Quantit\u00e0 per unit\u00e0<\/td>\n | 100 mg per 3 ml pen<\/td>\n<\/tr>\n | Quantity per package<\/td>\n | 1 pen, 10 pen needles and alcohol wipes<\/td>\n<\/tr>\n | Magazzinaggio<\/td>\n | Refrigerated at 2\u20138 \u00b0C, store in a dark place.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n | Forma, manipolazione e stoccaggio<\/h2>\nThe compound is dissolved in a sealed 3 ml glass cartridge in a pen with a click mechanism. A separate dissolution step is not required with this version; the cartridge remains closed until a needle is inserted. The label includes a table showing the relationship between click settings and dispensed volume, allowing sample collections to be reproducibly recorded in a protocol.<\/p>\n Store the pen refrigerated between 2 and 8 \u00b0C, protected from light and in the original packaging. Handle the pen in a clean working environment, use a new sterile needle for each draw to prevent cross-contamination, and wear standard personal protective equipment. Keep the material out of reach of unauthorized persons.<\/p>\n Composizione e risultati di laboratorio<\/h2>\nThe raw material used has a controlled purity of \u2265 99% (HPLC). The pen contains GHK-Cu in a sterile aqueous base; the total amount of active substance is stated on the label for each version.<\/p>\n |