{"id":3001,"date":"2026-09-01T09:43:28","date_gmt":"2026-09-01T09:43:28","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=3001"},"modified":"2026-09-02T14:07:35","modified_gmt":"2026-09-02T14:07:35","slug":"aod-9604","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/fr\/product\/aod-9604\/","title":{"rendered":"DOC-9604"},"content":{"rendered":"<h2>What is AOD-9604?<\/h2>\n<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues with the sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe. The chain consists of the fifteen residues of a defined C-terminal fragment of a longer, naturally occurring polypeptide chain, supplemented by one additional tyrosine at the N-terminal position. The compound is known under CAS number 221231-10-3, with the molecular formula C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> (approximately 1815.1 g\/mol) and PubChem CID 71300630.<\/p>\n<p>The spatial structure is determined by the two cysteine \u200b\u200bresidues at positions 7 and 15, which form a disulfide bridge with each other. This bridge closes part of the sequence into a loop, giving the chain in solution a significantly more limited conformation range than a fully open chain of comparable length. The combination of a short, fully written-out sequence and exactly one internal bridge makes AOD-9604 a highly reproducible model compound in comparative peptide research: the closed and reduced forms differ by two mass units and can be separated chromatographically, making the substance useful in research into the formation, opening, and reoxidation of disulfide bridges.<\/p>\n<h2>Applications dans un contexte de laboratoire<\/h2>\n<p>Within peptide chemistry and analytical work, AOD-9604 occurs in the following in vitro research areas, among others:<\/p>\n<ul>\n<li><strong>recherche sur les relations structure-activit\u00e9<\/strong> to the contribution of the added N-terminal tyrosine and of both cysteine \u200b\u200bpositions to chain conformation, charge distribution, and chromatographic behavior.<\/li>\n<li><strong>Recherche en chimie des peptides<\/strong> towards solubility and aggregation tendency of short chains closed by a disulfide bridge in aqueous and mixed media.<\/li>\n<li><strong>\u00c9tudes de stabilit\u00e9 enzymatique<\/strong> dans laquelle la rupture de la cha\u00eene est surveill\u00e9e dans des conditions de pH, de temp\u00e9rature et d'enzymes d\u00e9finies, et les fragments form\u00e9s sont caract\u00e9ris\u00e9s par spectrom\u00e9trie de masse.<\/li>\n<li><strong>D\u00e9veloppement et validation de m\u00e9thodes analytiques<\/strong> (HPLC, LC-MS, peptide mapping) where the tyrosine residue provides a usable UV signal and the closed form serves as a reference peak alongside the reduced variant.<\/li>\n<\/ul>\n<h2>Caract\u00e9ristiques<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>\u00c9chantillon<\/strong><\/td>\n<td>AOD-9604 (synthetic peptide), freeze-dried in sealed vial<\/td>\n<\/tr>\n<tr>\n<td><strong>Longueur du peptide<\/strong><\/td>\n<td>16 amino acid residues<\/td>\n<\/tr>\n<tr>\n<td><strong>S\u00e9quence<\/strong><\/td>\n<td>Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide bridge Cys7\u2013Cys15)<\/td>\n<\/tr>\n<tr>\n<td><strong>Num\u00e9ro CAS<\/strong><\/td>\n<td>221231-10-3<\/td>\n<\/tr>\n<tr>\n<td><strong>Formule mol\u00e9culaire \/ masse mol\u00e9culaire<\/strong><\/td>\n<td>C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> \/ approximately 1815.1 g\/mol<\/td>\n<\/tr>\n<tr>\n<td><strong>Classe<\/strong><\/td>\n<td>Synthetic linear peptide with intramolecular disulfide bridge<\/td>\n<\/tr>\n<tr>\n<td><strong>Formulaire<\/strong><\/td>\n<td>Poudre lyophilis\u00e9e dans un flacon en verre scell\u00e9<\/td>\n<\/tr>\n<tr>\n<td><strong>Puret\u00e9<\/strong><\/td>\n<td>\u2265 99 % (HPLC)<\/td>\n<\/tr>\n<tr>\n<td><strong>Stockage<\/strong><\/td>\n<td>Lyophilis\u00e9 \u00e0 2\u20138 \u00b0C, \u00e0 l'abri de la lumi\u00e8re et sec<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Forme, manipulation et stockage<\/h2>\n<p>The material is supplied as freeze-dried powder (lyophilisate), white to off-white in color, in a sealed glass vial with a rubber septum and aluminum shrink cap. Short peptide lyophilisate is hygroscopic; therefore, the vial remains closed in the original packaging until the sample is taken into processing in the laboratory.<\/p>\n<p>Store the sealed vial freeze-dried at 2\u20138 \u00b0C, in a dark and dry place. The usual laboratory precautions apply: work in a clean, dry environment, avoid repeated temperature changes, and record the batch number and opening date for each vial in the lab logbook so that measurement series remain traceable afterwards. For chains containing a disulfide bridge, contact with reducing agents requires extra attention, as this alters the conformational profile of the sample.<\/p>\n<h2>qualit\u00e9 analytique<\/h2>\n<p>In comparative peptide analysis, the purity of the starting material determines how reliably the measurement results can be interpreted: shortened sequences and degradation products generate additional chromatographic peaks that may coincide with the main component. Our AOD-9604 is supplied with a purity of \u2265 99%, determined by HPLC analysis in accordance with the accompanying Certificate of Analysis. The available Certificates of Analysis can be viewed on our website. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">page de r\u00e9sultats de laboratoire<\/a>.<\/p>\n<h2>Avertissement important<\/h2>\n<p>Ce produit est exclusivement destin\u00e9 \u00e0 la recherche et aux analyses en laboratoire. Il n'est pas destin\u00e9 \u00e0 des fins diagnostiques ou th\u00e9rapeutiques, et ne doit en aucun cas \u00eatre utilis\u00e9 chez l'homme ou l'animal. Ce produit n'est ni un aliment, ni un compl\u00e9ment alimentaire, ni un produit cosm\u00e9tique, ni un m\u00e9dicament. En achetant ce produit, l'acheteur confirme \u00eatre \u00e2g\u00e9 de 18 ans ou plus et s'engage \u00e0 l'utiliser exclusivement dans un environnement de recherche ou de laboratoire contr\u00f4l\u00e9.<\/p>","protected":false},"excerpt":{"rendered":"<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues (C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub>, approximately 1815.1 g\/mol) with an intramolecular disulfide bridge between the cysteine \u200b\u200bresidues at positions 7 and 15. Within scientific research, it is studied as a model compound in peptide chemistry and analytical work. Intended exclusively for laboratory and research purposes; not for human or animal use. Not a medicinal product.<\/p>","protected":false},"featured_media":3309,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[117,121],"product_tag":[],"class_list":["post-3001","product","type-product","status-publish","has-post-thumbnail","product_cat-metabool-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product\/3001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/comments?post=3001"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product\/3001\/revisions"}],"predecessor-version":[{"id":3061,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product\/3001\/revisions\/3061"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/media\/3309"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/media?parent=3001"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product_brand?post=3001"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product_cat?post=3001"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product_tag?post=3001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}