GHK-Cu is a naturally occurring metallopeptide, chemically a coordination complex of the tripeptide glycyl-L-histidyl-L-lysine with a copper(II) ion. In scientific research, it is studied as a model compound for metal-peptide coordination chemistry and as a reference standard in analytical work. This compound is offered as a kit containing 100 mg of freeze-dried lyophilisate and associated laboratory materials, exclusively for laboratory and research purposes.<\/p>\n
GHK-Cu (glycyl-L-histidyl-L-lysine-copper(II), also referred to in the literature as copper tripeptide-1 or prezatide-copper) consists of a short chain of glycine, histidine, and lysine that jointly coordinate one copper(II) ion. The metal ion is bound via the imidazole ring of histidine, the terminal amino group of glycine, and the intervening peptide bond; the free tripeptide itself has the formula C14<\/sub>H24<\/sub>N6<\/sub>O4<\/sub> (340.38 Da). This sharply defined coordination makes the compound a widely used model system in bioinorganic chemistry: stable enough to isolate, labile enough to study copper transfer measurably.<\/p>\n In research models, GHK-Cu is primarily investigated in its role as a copper carrier. In vitro, the complex functions as an exchangeable reservoir from which copper(II) is transferred to copper-binding proteins and copper-dependent enzymes such as lysyl oxidase and superoxide dismutase; the redox chemistry of the bound metal ion is a recurring area of \u200b\u200binterest in cell-free systems. In cell models, gene expression profiles are mapped, in which the peptide part and the metal ion stand opposite each other as separate variables. Consequently, GHK-Cu is used within scientific research as a model compound and reference substance.<\/p>\n In een laboratoriumcontext komt GHK-Cu onder meer voor in de volgende onderzoeksrichtingen:<\/p>\n Chacune de ces applications implique des recherches contr\u00f4l\u00e9es en laboratoire ou sur des mod\u00e8les pr\u00e9cliniques.<\/p>\n GHK-Cu falls under the category of nasal spray kits within our range: formulations in which a freeze-dried lyophilisate, a sterile saline solution, and an empty spray bottle are supplied as a single complete set. While GHK-Cu focuses on the coordination and transfer of a metal ion, other components within the same product line have been specifically chosen to cover receptor-bound or enzymatic targets. They share the kit format but differ fundamentally in molecular class and investigated mechanism.<\/p>\n The kit contains 100 mg GHK-Cu as freeze-dried lyophilisate in a sealed vial, together with a sterile saline solution and an empty spray bottle. Unlike solid tablet forms, reconstitution is required for a lyophilisate: the material is dissolved prior to analytical work. The powder is light blue to blue-violet, characteristic of copper(II) peptide complexes.<\/p>\n Store the unopened vial in a cool, dry, and dark place in the original packaging; in dissolved form, the material should be kept refrigerated at 2\u20138 \u00b0C. Handle the compound with the usual laboratory precautions: work in a clean environment, use appropriate protective equipment, and prevent cross-contamination. Metallopeptides are sensitive to repeated temperature changes. Keep the kit out of reach of unauthorized persons.<\/p>\n The lyophilisate in this kit has a controlled purity of \u2265 99% (HPLC). The saline solution and the spray bottle are laboratory accessories and do not contain any active compound themselves.<\/p>\nDomaines de recherche<\/h2>\n
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GHK-Cu binnen ons onderzoeksassortiment<\/h2>\n
Caract\u00e9ristiques<\/h2>\n
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\n \nSp\u00e9cification<\/th>\n Valeur<\/th>\n<\/tr>\n<\/thead>\n \n \u00c9chantillon<\/td>\n GHK-Cu<\/td>\n<\/tr>\n \n Synonymes<\/td>\n Glycyl-L-histidyl-L-lysine-copper(II); copper tripeptide-1; prezatide copper<\/td>\n<\/tr>\n \n Num\u00e9ro CAS<\/td>\n 89030-95-5 (copper complex); 49557-75-7 (free tripeptide)<\/td>\n<\/tr>\n \n Formule mol\u00e9culaire \/ masse mol\u00e9culaire<\/td>\n C14<\/sub>H23<\/sub>CuN6<\/sub>O4<\/sub> (cation) \/ 402.92 Da<\/td>\n<\/tr>\n \n PubChem CID<\/td>\n 71587328 (copper complex); 73587 (free tripeptide)<\/td>\n<\/tr>\n \n Classe<\/td>\n Tripeptide-copper(II) complex (metallopeptide)<\/td>\n<\/tr>\n \n Forme<\/td>\n Kit: freeze-dried lyophilisate, saline solution and spray bottle<\/td>\n<\/tr>\n \n Quantit\u00e9 par unit\u00e9<\/td>\n 100 mg per vial<\/td>\n<\/tr>\n \n Quantit\u00e9 par emballage<\/td>\n 1 complete kit<\/td>\n<\/tr>\n \n Stockage<\/td>\n Freeze-dried, cool and dark; in dissolved form refrigerated at 2\u20138 \u00b0C<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Forme, manipulation et stockage<\/h2>\n
Composition et r\u00e9sultats de laboratoire<\/h2>\n