{"id":2293,"date":"2026-09-01T08:52:01","date_gmt":"2026-09-01T08:52:01","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2293"},"modified":"2026-09-02T12:19:58","modified_gmt":"2026-09-02T12:19:58","slug":"alprostadil-20mcg","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/fr\/product\/alprostadil-20mcg\/","title":{"rendered":"Alprostadil 20 mcg"},"content":{"rendered":"<p>Alprostadil is an eicosanoid, chemically the synthetic form of prostaglandin E.<sub>1<\/sub>: a C<sub>20<\/sub>-carboxylic acid with a substituted cyclopentanone ring. Within scientific research, it is studied as a model compound for prostanoid receptors and eicosanoid chemistry and as a reference standard in analytical work. This compound is offered as a freeze-dried powder of 20 mcg per sealed vial, exclusively for laboratory and research purposes.<\/p>\n<h2>What is Alprostadil?<\/h2>\n<p>Alprostadil, systematic (13<em>E<\/em>,15<em>S<\/em>)-11\u03b1,15-dihydroxy-9-oxoprost-13-enoic acid, is composed of a five-membered ring with a ketone group at position 9 and two long side chains: a saturated chain with a terminal carboxylic acid group and a chain with one <em>trans<\/em>-double bond and a hydroxyl group in the S-configuration at position 15. The compound is distinct from prostaglandin E<sub>2<\/sub> due to the absence of the double bond between C5 and C6: one structural difference, making the molecule suitable for investigating the influence of side-chain unsaturation on receptor recognition. Chemically, it is a labile molecule: the combination of a \u03b2-hydroxyketone in the ring and an allylic hydroxyl group makes the structure susceptible to water loss and isomerization, successively producing prostaglandin A<sub>1<\/sub> and the conjugated prostaglandin B<sub>1<\/sub> arise. Consequently, the compound serves as a classic model in stability studies of prostanoids.<\/p>\n<p>In research models, prostaglandin E intervenes<sub>1<\/sub> It attaches to the EP receptor family: four G-protein-coupled subtypes (EP1 to EP4) that activate diverse pathways, including cAMP enhancement via Gs and calcium mobilization via Gq. This makes the compound a common reference ligand for mapping subtype selectivity. Enzymatically, the 15-hydroxyl group is oxidized to a keto group by 15-hydroxyprostaglandin dehydrogenase, which significantly reduces affinity; this rapid conversion makes the substance attractive for enzymological research. Consequently, Alprostadil is used as a model compound and reference substance in scientific research.<\/p>\n<h2>Domaines de recherche<\/h2>\n<p>In a laboratory context, Alprostadil occurs in the following research areas, among others:<\/p>\n<ul>\n<li>Binding studies of the EP1 to EP4 subtypes in cell lines and membrane preparations in vitro.<\/li>\n<li>Research into signal transduction: cAMP formation and calcium mobilization after receptor activation in cell models.<\/li>\n<li>Enzymological investigation of 15-hydroxyprostaglandin dehydrogenase and the oxidation of the 15-hydroxyl group.<\/li>\n<li>Model research into vascular tone in isolated tissue preparations, with the compound as a comparison standard.<\/li>\n<li>Structure-activity research within the prostanoids, focusing on the stereochemistry at positions 11 and 15.<\/li>\n<li>Stability studies regarding water separation and isomerization, and analytical method development using LC-MS\/MS, are necessary because the molecule itself exhibits hardly any UV absorption.<\/li>\n<\/ul>\n<p>Chacune de ces applications implique des recherches contr\u00f4l\u00e9es en laboratoire ou sur des mod\u00e8les pr\u00e9cliniques.<\/p>\n<h2>Alprostadil in our research assortment<\/h2>\n<p>Alprostadil falls under the category of freeze-dried research compounds in sealed vials within our product range. While Alprostadil is a lipid signaling molecule that targets prostanoid receptors, other components within the same product line focus on peptide chains or enzymatic targets. They share the freeze-dried form and associated storage requirements, but differ fundamentally in molecular class and investigated mechanism.<\/p>\n<h2>Caract\u00e9ristiques<\/h2>\n<table>\n<thead>\n<tr>\n<th>Sp\u00e9cification<\/th>\n<th>Valeur<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u00c9chantillon<\/td>\n<td>Alprostadil<\/td>\n<\/tr>\n<tr>\n<td>Synonymes<\/td>\n<td>Prostaglandin E<sub>1<\/sub>; PGE<sub>1<\/sub>; (13<em>E<\/em>,15<em>S<\/em>)-11\u03b1,15-dihydroxy-9-oxoprost-13-enoic acid<\/td>\n<\/tr>\n<tr>\n<td>Num\u00e9ro CAS<\/td>\n<td>745-65-3<\/td>\n<\/tr>\n<tr>\n<td>Formule mol\u00e9culaire \/ masse mol\u00e9culaire<\/td>\n<td>C<sub>20<\/sub>H<sub>34<\/sub>O<sub>5<\/sub> \/ 354.5 Da<\/td>\n<\/tr>\n<tr>\n<td>PubChem CID<\/td>\n<td>5280723<\/td>\n<\/tr>\n<tr>\n<td>Classe<\/td>\n<td>Eicosanoid, prostaglandin; ligand of the EP receptor family<\/td>\n<\/tr>\n<tr>\n<td>Forme<\/td>\n<td>Freeze-dried powder (lyophilisate)<\/td>\n<\/tr>\n<tr>\n<td>Quantit\u00e9 par flacon<\/td>\n<td>20 mcg<\/td>\n<\/tr>\n<tr>\n<td>Stockage<\/td>\n<td>Store freeze-dried in a cool, dark place; use refrigerated and for a short period when in solution.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Forme, manipulation et stockage<\/h2>\n<p>Alprostadil is supplied as a freeze-dried powder in a sealed vial with 20 mcg per unit. The lyophilisate is a solid, fine mass that is only dissolved in the laboratory setup, according to the laboratory's own procedure; in analytical work, prostaglandins are usually dissolved in ethanol or a similar organic medium, because aqueous solutions accelerate chemical degradation.<\/p>\n<p>Store the unopened vial in a cool, dry, and dark place in the original packaging; the structure is sensitive to heat, moisture, and non-neutral acidity. Handle the material with standard laboratory precautions: work in a clean environment, use appropriate personal protective equipment, and prevent cross-contamination with other research materials. Keep the packaging out of reach of unauthorized persons.<\/p>\n<h2>Composition et r\u00e9sultats de laboratoire<\/h2>\n<p>The material in the vial is the freeze-dried compound with a controlled purity of \u2265 99% (HPLC). For this class of substances, chromatographic separation also reveals the dehydration and isomerization products that arise during improper storage.<\/p>\n<p>Vous trouverez un aper\u00e7u de la documentation analytique disponible sur notre site web. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">page de r\u00e9sultats de laboratoire<\/a>Les rapports sont centralis\u00e9s \u00e0 cet endroit, ce qui vous permet d'int\u00e9grer les donn\u00e9es \u00e0 vos propres archives de recherche.<\/p>\n<h2>Foire aux questions<\/h2>\n<p><strong>To which class of substances does Alprostadil belong?<\/strong><br \/>Alprostadil is an eicosanoid: a lipid signaling molecule with twenty carbon atoms from the prostaglandin family. It is not a peptide and therefore contains no amino acid sequence.<\/p>\n<p><strong>What happens to the 15-hydroxyl group in research models?<\/strong><br \/>That group is oxidized to a keto group by 15-hydroxyprostaglandin dehydrogenase. The resulting 15-keto product binds much more weakly to the EP receptors, making this step central to mechanistic research on prostanoids.<\/p>\n<p><strong>Sous quelle forme le compos\u00e9 est-il fourni ?<\/strong><br \/>As freeze-dried powder in a sealed vial, with 20 mcg per vial.<\/p>\n<p><strong>Comment conserver le flacon ?<\/strong><br \/>Cool, dry, and dark, in the original packaging. The freeze-dried powder is significantly more stable than a solution; solutions are stored refrigerated and preferably used shortly after preparation.<\/p>","protected":false},"excerpt":{"rendered":"<p>Alprostadil 20mcg: freeze-dried powder in a sealed vial.<\/p>","protected":false},"featured_media":3276,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[119,121],"product_tag":[],"class_list":["post-2293","product","type-product","status-publish","has-post-thumbnail","product_cat-hormonaal-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product\/2293","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/comments?post=2293"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product\/2293\/revisions"}],"predecessor-version":[{"id":2355,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product\/2293\/revisions\/2355"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/media\/3276"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/media?parent=2293"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product_brand?post=2293"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product_cat?post=2293"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/fr\/wp-json\/wp\/v2\/product_tag?post=2293"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}