{"id":3001,"date":"2026-09-01T09:43:28","date_gmt":"2026-09-01T09:43:28","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=3001"},"modified":"2026-09-02T14:07:35","modified_gmt":"2026-09-02T14:07:35","slug":"aod-9604","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/es\/product\/aod-9604\/","title":{"rendered":"AOD-9604"},"content":{"rendered":"<h2>What is AOD-9604?<\/h2>\n<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues with the sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe. The chain consists of the fifteen residues of a defined C-terminal fragment of a longer, naturally occurring polypeptide chain, supplemented by one additional tyrosine at the N-terminal position. The compound is known under CAS number 221231-10-3, with the molecular formula C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> (approximately 1815.1 g\/mol) and PubChem CID 71300630.<\/p>\n<p>The spatial structure is determined by the two cysteine \u200b\u200bresidues at positions 7 and 15, which form a disulfide bridge with each other. This bridge closes part of the sequence into a loop, giving the chain in solution a significantly more limited conformation range than a fully open chain of comparable length. The combination of a short, fully written-out sequence and exactly one internal bridge makes AOD-9604 a highly reproducible model compound in comparative peptide research: the closed and reduced forms differ by two mass units and can be separated chromatographically, making the substance useful in research into the formation, opening, and reoxidation of disulfide bridges.<\/p>\n<h2>Aplicaciones en un contexto de laboratorio<\/h2>\n<p>Within peptide chemistry and analytical work, AOD-9604 occurs in the following in vitro research areas, among others:<\/p>\n<ul>\n<li><strong>Investigaci\u00f3n sobre la relaci\u00f3n estructura-actividad<\/strong> to the contribution of the added N-terminal tyrosine and of both cysteine \u200b\u200bpositions to chain conformation, charge distribution, and chromatographic behavior.<\/li>\n<li><strong>Investigaci\u00f3n en qu\u00edmica de p\u00e9ptidos<\/strong> towards solubility and aggregation tendency of short chains closed by a disulfide bridge in aqueous and mixed media.<\/li>\n<li><strong>Estudios de estabilidad enzim\u00e1tica<\/strong> En este m\u00e9todo, se monitoriza la degradaci\u00f3n de la cadena bajo condiciones definidas de pH, temperatura y enzimas, y los fragmentos formados se caracterizan mediante espectrometr\u00eda de masas.<\/li>\n<li><strong>Desarrollo y validaci\u00f3n de m\u00e9todos anal\u00edticos<\/strong> (HPLC, LC-MS, peptide mapping) where the tyrosine residue provides a usable UV signal and the closed form serves as a reference peak alongside the reduced variant.<\/li>\n<\/ul>\n<h2>Presupuesto<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Muestra<\/strong><\/td>\n<td>AOD-9604 (synthetic peptide), freeze-dried in sealed vial<\/td>\n<\/tr>\n<tr>\n<td><strong>Longitud del p\u00e9ptido<\/strong><\/td>\n<td>16 amino acid residues<\/td>\n<\/tr>\n<tr>\n<td><strong>Secuencia<\/strong><\/td>\n<td>Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide bridge Cys7\u2013Cys15)<\/td>\n<\/tr>\n<tr>\n<td><strong>N\u00famero CAS<\/strong><\/td>\n<td>221231-10-3<\/td>\n<\/tr>\n<tr>\n<td><strong>F\u00f3rmula molecular \/ peso<\/strong><\/td>\n<td>C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub> \/ approximately 1815.1 g\/mol<\/td>\n<\/tr>\n<tr>\n<td><strong>Clase<\/strong><\/td>\n<td>Synthetic linear peptide with intramolecular disulfide bridge<\/td>\n<\/tr>\n<tr>\n<td><strong>Forma<\/strong><\/td>\n<td>Polvo liofilizado en un vial de vidrio sellado.<\/td>\n<\/tr>\n<tr>\n<td><strong>Pureza<\/strong><\/td>\n<td>\u2265 99% (HPLC)<\/td>\n<\/tr>\n<tr>\n<td><strong>Almacenamiento<\/strong><\/td>\n<td>Liofilizado a 2\u20138 \u00b0C, oscuro y seco.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Forma, manipulaci\u00f3n y almacenamiento<\/h2>\n<p>The material is supplied as freeze-dried powder (lyophilisate), white to off-white in color, in a sealed glass vial with a rubber septum and aluminum shrink cap. Short peptide lyophilisate is hygroscopic; therefore, the vial remains closed in the original packaging until the sample is taken into processing in the laboratory.<\/p>\n<p>Store the sealed vial freeze-dried at 2\u20138 \u00b0C, in a dark and dry place. The usual laboratory precautions apply: work in a clean, dry environment, avoid repeated temperature changes, and record the batch number and opening date for each vial in the lab logbook so that measurement series remain traceable afterwards. For chains containing a disulfide bridge, contact with reducing agents requires extra attention, as this alters the conformational profile of the sample.<\/p>\n<h2>Calidad anal\u00edtica<\/h2>\n<p>In comparative peptide analysis, the purity of the starting material determines how reliably the measurement results can be interpreted: shortened sequences and degradation products generate additional chromatographic peaks that may coincide with the main component. Our AOD-9604 is supplied with a purity of \u2265 99%, determined by HPLC analysis in accordance with the accompanying Certificate of Analysis. The available Certificates of Analysis can be viewed on our website. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">p\u00e1gina de resultados de laboratorio<\/a>.<\/p>\n<h2>Aviso importante<\/h2>\n<p>Este producto se suministra exclusivamente para investigaci\u00f3n de laboratorio y an\u00e1lisis. No est\u00e1 destinado a aplicaciones diagn\u00f3sticas ni terap\u00e9uticas, y est\u00e1 expresamente prohibido su uso en humanos o animales. Este producto no es un alimento, un suplemento, un producto cosm\u00e9tico ni un medicamento registrado. Al adquirir este producto, el comprador confirma ser mayor de 18 a\u00f1os y que lo utilizar\u00e1 exclusivamente en un entorno controlado de investigaci\u00f3n o laboratorio.<\/p>","protected":false},"excerpt":{"rendered":"<p>AOD-9604 is a synthetic linear peptide of sixteen amino acid residues (C<sub>78<\/sub>H<sub>123<\/sub>N<sub>23<\/sub>O<sub>23<\/sub>S<sub>2<\/sub>, approximately 1815.1 g\/mol) with an intramolecular disulfide bridge between the cysteine \u200b\u200bresidues at positions 7 and 15. Within scientific research, it is studied as a model compound in peptide chemistry and analytical work. Intended exclusively for laboratory and research purposes; not for human or animal use. Not a medicinal product.<\/p>","protected":false},"featured_media":3309,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[117,121],"product_tag":[],"class_list":["post-3001","product","type-product","status-publish","has-post-thumbnail","product_cat-metabool-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product\/3001","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/comments?post=3001"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product\/3001\/revisions"}],"predecessor-version":[{"id":3061,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product\/3001\/revisions\/3061"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/media\/3309"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/media?parent=3001"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product_brand?post=3001"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product_cat?post=3001"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product_tag?post=3001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}