{"id":2653,"date":"2026-09-01T09:18:34","date_gmt":"2026-09-01T09:18:34","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2653"},"modified":"2026-09-02T12:20:09","modified_gmt":"2026-09-02T12:20:09","slug":"cortagen-20mg","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/es\/product\/cortagen-20mg\/","title":{"rendered":"Cortagen 20 mg"},"content":{"rendered":"<h2>Descripci\u00f3n<\/h2>\n<p>Cortagen is a synthetic tetrapeptide bioregulator with the sequence Ala-Glu-Asp-Pro (AEDP), developed within the Khavinson research line at the St. Petersburg Institute of Bioregulation and Gerontology. The peptide was synthesized based on amino acid analysis of <em>cortexin<\/em>, a polypeptide preparation derived from cerebral cortex with documented neurotrophic activity, and represents a simplified, targeted version of the active components therein.<\/p>\n<h2>Tabla de especificaciones<\/h2>\n<table>\n<tbody>\n<tr>\n<th>Especificaci\u00f3n<\/th>\n<th>Valor<\/th>\n<\/tr>\n<tr>\n<td>Muestra<\/td>\n<td>Cortagen (Ala-Glu-Asp-Pro)<\/td>\n<\/tr>\n<tr>\n<td>Clase<\/td>\n<td>Khavinson tetrapeptide bioregulator (cytogen)<\/td>\n<\/tr>\n<tr>\n<td>F\u00f3rmula molecular \/ peso<\/td>\n<td>C\u2081\u2087H\u2082\u2086N\u2084O\u2089 \/ 430.41 Da<\/td>\n<\/tr>\n<tr>\n<td>Secuencia<\/td>\n<td>Ala-Glu-Asp-Pro (AEDP)<\/td>\n<\/tr>\n<tr>\n<td>Forma<\/td>\n<td>Polvo liofilizado (polvo seco)<\/td>\n<\/tr>\n<tr>\n<td>Condiciones de almacenamiento<\/td>\n<td>Mantener refrigerado, protegido de la luz y la humedad.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Relevancia de la investigaci\u00f3n<\/h2>\n<ul>\n<li><strong>Cerebral cortex<\/strong> \u2014 derived from cortical analysis, classically studied in models for cortical neurons and glial cells.<\/li>\n<li><strong>Chromatin interaction<\/strong> \u2014 In vitro studies suggest AACC as a preferred DNA-binding motif, which aligns with the broader Khavinson hypothesis of sequence-specific gene expression modulation.<\/li>\n<li><strong>Inflammatory balance in CNS<\/strong> \u2014 preclinical data regarding pro- and anti-oxidative processes and interleukin-2 expression.<\/li>\n<li><strong>Neuroregeneration<\/strong> \u2014 research interest regarding ischemic brain injury recovery and nerve regeneration models.<\/li>\n<\/ul>\n<h2>Preguntas frecuentes<\/h2>\n<p><strong>What is Cortagen?<\/strong><br \/>A tetrapeptide bioregulator (AEDP) from the Khavinson school, designed based on cortexin amino acid analysis, specifically for research into cortical and neuronal tissue.<\/p>\n<p><strong>How does cortagen interact with cells?<\/strong><br \/>Due to its low molecular weight (430 Da), the peptide can cross cell and nuclear membranes and engage in direct interactions with chromatin; in vitro studies indicate AACC as a preferential DNA-binding motif.<\/p>\n<p><strong>How is Cortagen stored?<\/strong><br \/>Store the lyophilisate refrigerated (2\u20138 \u00b0C), protected from light and moisture.<\/p>\n<blockquote>\n<p><strong>Descargo de responsabilidad:<\/strong> Destinado exclusivamente a fines de investigaci\u00f3n. No apto para consumo humano ni animal, ni para uso m\u00e9dico, diagn\u00f3stico, terap\u00e9utico o cosm\u00e9tico. El comprador debe ser mayor de 18 a\u00f1os y confirmar el contexto de la investigaci\u00f3n.<\/p>\n<\/blockquote>","protected":false},"excerpt":{"rendered":"<p><strong>Cortagen<\/strong> is a synthetic tetrapeptide bioregulator with the sequence Ala-Glu-Asp-Pro (AEDP), developed within the Khavinson research line at the St. Petersburg Institute of Bioregulation and Gerontology. The peptide was synthesized based on amino acid analysis of <em>cortexin<\/em>, a polypeptide preparation derived from cerebral cortex with documented neurotrophic activity, and represents a simplified, targeted version of the active components therein.<\/p>","protected":false},"featured_media":3278,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[122,121],"product_tag":[],"class_list":["post-2653","product","type-product","status-publish","has-post-thumbnail","product_cat-cognitief","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product\/2653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/comments?post=2653"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product\/2653\/revisions"}],"predecessor-version":[{"id":2730,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product\/2653\/revisions\/2730"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/media\/3278"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/media?parent=2653"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product_brand?post=2653"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product_cat?post=2653"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/es\/wp-json\/wp\/v2\/product_tag?post=2653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}