Vitamin B12 (cobalamin) is a water-soluble cobalt-corrinoid compound, chemically an organometallic complex with a central cobalt ion in a corrine ring system. In scientific research, it is studied as a model compound for cofactor-linked enzyme catalysis and as a reference standard in analytical work. This compound is offered as a ready-to-use 10 ml solution containing 10 mg, exclusively for laboratory and research purposes.<\/p>\n
Cobalamin is the collective name for a group of corrinoids of which cyanocobalamin (C63<\/sub>H88<\/sub>CoN14<\/sub>O14<\/sub>P) is the generally recognized reference form of the class. The molecule consists of a corrine ring of four pyrrole rings containing a central cobalt ion, a nucleotide side chain with 5,6-dimethylbenzimidazole as the lower axial ligand, and an interchangeable upper axial ligand that distinguishes the cobalamin forms. This combination of a transition metal in a macrocyclic environment with an interchangeable coordination position makes the compound a widely used model in bioinorganic chemistry.<\/p>\n In research models, cobalamin derives its significance primarily from the cobalt-carbon bond, the only organometallic bond described in the biochemistry of living systems. In vitro, the derived forms methylcobalamin and adenosylcobalamin function as cofactors for methionine synthase and methylmalonyl-CoA mutase, respectively\u2014two enzymes used in cell models to study methyl transfer and radical-mediated rearrangement reactions. Furthermore, the cobalt-carbon bond is photosensitive and can be homolytically cleaved under controlled illumination, making the compound suitable for photochemical and spectroscopic modeling. Consequently, Vitamin B12 is used as a model compound and reference substance within scientific research.<\/p>\n In a laboratory context, Vitamin B12 occurs in the following research areas, among others:<\/p>\n Each of these applications involves controlled laboratory or preclinical model research.<\/p>\n Vitamin B12 falls within our range under the ready-to-use liquid research solutions in vials, a category distinct from the freeze-dried powder forms. While cobalamin focuses on metal-bound cofactor chemistry and enzyme catalysis, other components within the same product line have been specifically chosen to cover receptor-bound or signal transduction-oriented targets. These compounds share the liquid presentation form but differ fundamentally in molecular class and investigated mechanism.<\/p>\n Vitamin B12 is supplied as a ready-to-use aqueous solution in a 10 ml vial containing a total of 10 mg. Unlike freeze-dried compounds, reconstitution is not required with this form; the solution can be drawn directly from a laboratory setup for further analysis.<\/p>\n Store the vial refrigerated at 2\u20138 \u00b0C, in a dark place and protected from light, in the original packaging; corrinoids are photosensitive, so light protection requires special attention with this class of substances. Handle the compound with the usual laboratory precautions: work in a clean environment, use suitable personal protective equipment, and prevent cross-contamination with other research materials. Keep the packaging out of reach of unauthorized persons.<\/p>\n The starting material for this solution is selected for a controlled purity of \u2265 99% (HPLC). The content of the vial is expressed as the amount of substance per unit: 10 mg in 10 ml.<\/p>\nResearch areas<\/h2>\n
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Vitamin B12 in our research range<\/h2>\n
Specifications<\/h2>\n
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\n \nSpecification<\/th>\n Value<\/th>\n<\/tr>\n<\/thead>\n \n Sample<\/td>\n Vitamin B12 (cobalamin)<\/td>\n<\/tr>\n \n Synonyms<\/td>\n cyanocobalamin; cyanocob(III)alamin; CN-Cbl \u2014 as reference form of the cobalamin class<\/td>\n<\/tr>\n \n CAS number<\/td>\n 68-19-9 (cyanocobalamin)<\/td>\n<\/tr>\n \n Molecular formula \/ weight<\/td>\n C63<\/sub>H88<\/sub>CoN14<\/sub>O14<\/sub>P\/1355.4 Da (cyanocobalamin)<\/td>\n<\/tr>\n \n PubChem CID<\/td>\n 166596686 (cyanocobalamin)<\/td>\n<\/tr>\n \n Class<\/td>\n Water-soluble cobalt-corrinoid compound, not a peptide<\/td>\n<\/tr>\n \n Form<\/td>\n Ready-made solution in vial<\/td>\n<\/tr>\n \n Quantity per unit<\/td>\n 10 mg in 10 ml<\/td>\n<\/tr>\n \n Storage<\/td>\n Keep refrigerated at 2\u20138 \u00b0C, in a dark place and protected from light.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Shape, handling and storage<\/h2>\n
Composition and lab results<\/h2>\n