Adamax Nasal Spray Kit

For laboratory and research purposes only. Not for human or veterinary use.

Adamax is a synthetic, terminally modified peptide analog from the ACTH(4–10) peptide family that is studied in controlled laboratory settings within the context of peptide-mediated signaling pathways and molecular regulatory systems. In scientific research, the compound is used as a model compound and as a reference standard in analytical work. This research kit contains 5 mg of lyophilized lyophilisate in a sealed vial, with sterile physiological saline solution (NaCl 0.9%) and a spray bottle.

What is Adamax?

Adamax is constructed around the heptapeptide core sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP), itself derived from the ACTH(4–10) fragment. Terminal modifications have been added to this core: an N-terminal acetyl group and a modified C-terminal end. This shielding of both chain ends changes the charge profile of the molecule and reduces the binding capacity of exopeptidases to the terminal peptide bonds in in vitro systems. The literature is not conclusive regarding the exact composition of the C-terminal fragment; therefore, only verifiable structural data are listed below.

In research models, Adamax is studied in relation to peptide-mediated signaling pathways and molecular regulatory mechanisms in cell culture systems. Because the molecule shares a core sequence with a well-characterized reference compound but differs at both ends, it serves as comparison input in structure-activity relationship research: observed differences in analytical behavior are attributable to the terminal groups. Consequently, Adamax is used as a model compound and reference substance within scientific research.

Research areas

In a laboratory context, Adamax occurs in the following research areas:

• Structure-activity relationship research into terminally modified analogs of the ACTH(4–10) core sequence.
• Studies of peptide-mediated signaling pathways and molecular regulatory networks in controlled cell models in vitro.
• Influence of N-terminal acetylation on conformation, charge distribution, and solubility behavior of short peptide chains.
• Comparative stability study of the degradation rate of modified and unmodified chains in enzymatic in vitro assays.
• Receptor interaction modeling within the melanocortin-related peptide family under defined conditions.
• Analytical method development and validation (HPLC, LC-MS, UV detection) where the peptide serves as reference input.

Each of these applications involves controlled laboratory or preclinical model research.

Analytical specification

The material is submitted with a controlled purity of ≥ 99%, determined via high-pressure liquid chromatography (HPLC). Identity and purity are determining parameters in analytical peptide work: incompletely modified chains differ structurally only marginally from the target compound and can therefore be included in chromatographic measurements. Particularly for a molecule where the distinction lies in the terminal groups, purity determines whether an observed difference can be attributed to that modification. An overview of the available analysis documentation can be found on our website. lab results page.

Specifications

Shape, handling and storage

Adamax is supplied as 5 mg freeze-dried lyophilisate in a sealed vial, with saline solution and spray bottle. The lyophilization process preserves the molecular integrity of the peptide chain during storage and transport. The material is white to off-white; minor variations in the shape of the cake occur during freeze-drying and do not indicate quality or defect.

Store the sealed lyophilisate in a cool, dry, and dark place in the original packaging, protected from light and moisture; keep the remaining parts sealed until use. Observe the usual laboratory precautions: work in a clean environment, use appropriate personal protective equipment, prevent cross-contamination with other research materials, and keep the packaging out of reach of unauthorized persons. Dispose of residual material in accordance with applicable laboratory guidelines.

Adamax in our research range

Adamax falls under the category of freeze-dried investigational compounds supplied as a kit within our range. Researchers regularly combine the compound with other peptides that are studied via their own molecular target. While Adamax distinguishes itself through terminal modification of a short, well-characterized core sequence, other components within the same product line have been specifically chosen to cover metal-bound, receptor-bound, or enzymatic targets. They share the freeze-dried delivery form but differ in molecular class and investigated mechanism.

Frequently Asked Questions

To which class of substances does Adamax belong?
A synthetic peptide analog, constructed around the core sequence Met-Glu-His-Phe-Pro-Gly-Pro from the ACTH(4–10) family and featuring terminal modifications at both ends of the chain.

Why are the terminal modifications relevant in research?
They give the molecule a defined, well-characterizable profile that differs from a known reference sequence at exactly two points. This makes the compound useful in structure-activity relationship research and in comparative analytical methods.

What color is the material?
White to off-white. Small differences in the shape of the cake occur during freeze-drying and are normal.

What does the kit contain?
A sealed vial containing 5 mg of ≥ 99% lyophilisate (HPLC), sterile physiological saline solution (0.9% NaCl), and a spray bottle.

How do I store the material?
Store in a cool, dry, and dark place in the original packaging, protected from light and moisture.