{"id":2569,"date":"2026-09-01T09:11:04","date_gmt":"2026-09-01T09:11:04","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2569"},"modified":"2026-09-02T12:17:40","modified_gmt":"2026-09-02T12:17:40","slug":"pinealon-vial-20-mg","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/da\/product\/pinealon-vial-20-mg\/","title":{"rendered":"Pinealon h\u00e6tteglas 20 mg"},"content":{"rendered":"<p>Pinealon er et syntetisk kort peptid fra gruppen af Khavinson-bioregulatorer, kemisk et tripeptid opbygget af glutaminsyre, asparaginsyre og arginin. Inden for videnskabelig forskning unders\u00f8ges det som modelforbindelse for peptid-nukleinsyre-interaktion og som referencestandard i analytisk arbejde. Denne forbindelse tilbydes som fryset\u00f8rret pulver med 20 mg pr. h\u00e6tteglas, udelukkende til laboratorie- og forskningsform\u00e5l.<\/p>\n<h2>What is Pinealon?<\/h2>\n<p>Pinealon (L-alpha-glutamyl-L-alpha-aspartyl-L-arginine, sekvens Glu-Asp-Arg, i litteraturen kode EDR) er et line\u00e6rt tripeptid med molekylformlen C<sub>15<\/sub>H<sub>26<\/sub>N<sub>6<\/sub>O<sub>8<\/sub> og en molekylv\u00e6gt p\u00e5 418,40 Da. K\u00e6den kombinerer to sure sidek\u00e6der \u2014 glutaminsyre og asparaginsyre \u2014 med det st\u00e6rkt basiske arginin, s\u00e5 molekylet har b\u00e5de negativ og positiv ladningst\u00e6thed over en meget kort afstand. Denne ladningsfordeling i blot tre aminosyrer g\u00f8r forbindelsen til en ofte anvendt model for interaktionen mellem korte peptider og ladede biopolymerer.<\/p>\n<p>I forskningsmodeller unders\u00f8ges Pinealon som ligand for dobbeltstrenget DNA: spektroskopi og molekyl\u00e6r modellering beskriver, hvordan korte peptider med denne aminosyrekonfiguration in vitro retter sig mod bestemte nukleotidsekvenser i dobbeltspiralens store fure. I cellemodeller unders\u00f8ges det dern\u00e6st, om en s\u00e5dan binding h\u00e6nger sammen med \u00e6ndringer i kromatinets pakning \u2014 overgangen fra t\u00e6tpakket heterokromatin til mere tilg\u00e6ngeligt eukromatin \u2014 og dermed med transkriptionen af bestemte gener. Denne arbejdshypotese fra Khavinsons forskningslinje er hidtil is\u00e6r unders\u00f8gt in vitro og i pr\u00e6kliniske modeller. Inden for videnskabelig forskning anvendes Pinealon derfor som modelforbindelse og referencestof.<\/p>\n<h2>Forskningsomr\u00e5der<\/h2>\n<p>I en laboratoriekontekst optr\u00e6der Pinealon blandt andet inden for f\u00f8lgende forskningsomr\u00e5der:<\/p>\n<ul>\n<li>Biophysical research into the binding of short peptides to double-stranded DNA, measured using spectroscopic techniques in vitro.<\/li>\n<li>Molecular modeling studies of the structure-activity relationship of tripeptides with an acid-base charge profile.<\/li>\n<li>Epigenetically oriented modeling of chromatin packing and the accessibility of promoter regions.<\/li>\n<li>Gene expression research in cell culture systems, in which transcript levels are monitored in vitro.<\/li>\n<li>Analytical method development and validation (HPLC, LC-MS) using Pinealon as the reference standard.<\/li>\n<li>Stability and solubility studies of freeze-dried tripeptides under controlled conditions.<\/li>\n<\/ul>\n<p>Hver af disse anvendelser involverer kontrolleret laboratorie- eller pr\u00e6klinisk modelforskning.<\/p>\n<h2>Pinealon in our research assortment<\/h2>\n<p>Pinealon falls under the category of freeze-dried peptides in vial form within our range. Researchers in this category regularly combine the compound with other short peptides that are studied via their own biochemical target. While Pinealon focuses on the interaction between a short peptide and nucleic acids, other components in the same product line have been chosen to cover receptor-linked or enzymatic targets. These compounds share the freeze-dried form but differ fundamentally in chain length and investigated mechanism.<\/p>\n<h2>Specifikationer<\/h2>\n<table>\n<thead>\n<tr>\n<th>Specifikation<\/th>\n<th>V\u00e6rdi<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Pr\u00f8ve<\/td>\n<td>Pinealon<\/td>\n<\/tr>\n<tr>\n<td>Synonymer<\/td>\n<td>L-alpha-glutamyl-L-alpha-aspartyl-L-arginine; Glu-Asp-Arg; EDR peptide<\/td>\n<\/tr>\n<tr>\n<td>CAS-nummer<\/td>\n<td>175175-23-2<\/td>\n<\/tr>\n<tr>\n<td>Molekylformel \/ v\u00e6gt<\/td>\n<td>C<sub>15<\/sub>H<sub>26<\/sub>N<sub>6<\/sub>O<sub>8<\/sub> \/ 418.40 Da<\/td>\n<\/tr>\n<tr>\n<td>PubChem CID<\/td>\n<td>10273502<\/td>\n<\/tr>\n<tr>\n<td>Klasse<\/td>\n<td>Syntetisk tripeptid, kort peptidbioregulator (cytogen)<\/td>\n<\/tr>\n<tr>\n<td>Form<\/td>\n<td>Lyofilisat (fryset\u00f8rret pulver)<\/td>\n<\/tr>\n<tr>\n<td>M\u00e6ngde pr. h\u00e6tteglas<\/td>\n<td>20 mg<\/td>\n<\/tr>\n<tr>\n<td>Opbevaring<\/td>\n<td>Opbevares k\u00f8ligt, beskyttet mod lys og fugt<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Form, h\u00e5ndtering og opbevaring<\/h2>\n<p>Pinealon is supplied as a freeze-dried powder, standardized to 20 mg per vial. Unlike a solid tablet form, a lyophilisate is dissolved in a suitable solvent prior to analytical or cell culture work; the dry state serves the stability of the peptide chain during transport and storage.<\/p>\n<p>Store the unopened vial refrigerated, protected from direct light and moisture, in the original packaging; for longer periods, the dry lyophilisate should be stored frozen. Observe the compound with standard laboratory precautions: work in a clean environment, use appropriate personal protective equipment, and prevent cross-contamination with other research materials. Keep the packaging out of reach of unauthorized persons.<\/p>\n<h2>Sammens\u00e6tning og laboratorieresultater<\/h2>\n<p>This lyophilisate has a controlled purity of \u2265 99% (HPLC), determined on the peptide chain Glu-Asp-Arg. The vial contains exclusively the freeze-dried peptide.<\/p>\n<p>Du kan finde en oversigt over den tilg\u00e6ngelige analytiske dokumentation p\u00e5 vores <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">side med laboratorieresultater<\/a>Rapporterne samles centralt der, s\u00e5 du kan integrere dataene i dine egne forskningsregistre.<\/p>\n<h2>Ofte stillede sp\u00f8rgsm\u00e5l<\/h2>\n<p><strong>To which class of substances does Pinealon belong?<\/strong><br \/>Pinealon is a synthetic tripeptide with the sequence Glu-Asp-Arg and belongs to the short peptide bioregulators (cytogens) of the Khavinson research line. It is therefore not a small organic molecule, but an amino acid chain.<\/p>\n<p><strong>What is being investigated regarding the DNA interaction of Pinealon?<\/strong><br \/>In vitro studies using spectroscopy and molecular modeling describe how the EDR motif targets specific nucleotide sequences in the major groove of the double helix. In cell models, the question then is whether this binding is associated with looser chromatin packing and altered transcription \u2014 the central focus of mechanistic laboratory research into this connection.<\/p>\n<p><strong>I hvilken form leveres forbindelsen?<\/strong><br \/>As a freeze-dried powder of 20 mg per vial. A lyophilisate is dissolved in a suitable solvent prior to analytical or cell culture work.<\/p>\n<p><strong>Hvordan opbevarer jeg flasken?<\/strong><br \/>Refrigerated, protected from light and moisture, preferably in the original packaging.<\/p>","protected":false},"excerpt":{"rendered":"<p>Pinealon er en syntetisk tripeptid-bioregulator fra Khavinsons forskningslinje (cytogen-familien). Inden for forskning unders\u00f8ges Pinealon i modeller vedr\u00f8rende neuroner og hjernefunktion.<\/p>","protected":false},"featured_media":3255,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[122,120,121],"product_tag":[],"class_list":["post-2569","product","type-product","status-publish","has-post-thumbnail","product_cat-cognitief","product_cat-longevity-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/product\/2569","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/comments?post=2569"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/product\/2569\/revisions"}],"predecessor-version":[{"id":2646,"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/product\/2569\/revisions\/2646"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/media\/3255"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/media?parent=2569"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/product_brand?post=2569"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/product_cat?post=2569"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/da\/wp-json\/wp\/v2\/product_tag?post=2569"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}