{"id":2975,"date":"2026-09-01T09:41:15","date_gmt":"2026-09-01T09:41:15","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2975"},"modified":"2026-09-02T12:18:26","modified_gmt":"2026-09-02T12:18:26","slug":"ghrp-2-10mg","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/cs\/product\/ghrp-2-10mg\/","title":{"rendered":"GHRP-2 10 mg"},"content":{"rendered":"<p>GHRP-2 (Growth Hormone Releasing Peptide-2), tak\u00e9 zn\u00e1m\u00fd jako Pralmorelin, je syntetick\u00fd hexapeptid (\u0159et\u011bzec \u0161esti aminokyselin) a agonista ghrelinov\u00e9ho receptoru (GHSR-1a). Pat\u0159\u00ed do t\u0159\u00eddy sekretagog\u016f r\u016fstov\u00e9ho hormonu (sekretagogy GH: molekuly, kter\u00e9 aktivuj\u00ed uvol\u0148ov\u00e1n\u00ed r\u016fstov\u00e9ho hormonu z hypof\u00fdzy ve v\u00fdzkumn\u00fdch modelech) a pou\u017e\u00edv\u00e1 se ve v\u011bdeck\u00e9m v\u00fdzkumu jako modelov\u00e1 slou\u010denina pro neuroendokrinn\u00ed osu r\u016fstov\u00e9ho hormonu. GHRP-2 je nab\u00edzen v\u00fdhradn\u011b pro laboratorn\u00ed a v\u00fdzkumn\u00e9 \u00fa\u010dely.<\/p>\n<h2>Co je GHRP-2?<\/h2>\n<p>GHRP-2 je jeden z prvn\u00edch, pln\u011b syntetick\u00fdch peptidov\u00fdch sekretagog\u016f, kter\u00fd hraje \u00fast\u0159edn\u00ed roli ve v\u00fdzkumu osy hypotalamus-hypof\u00fdza. Slou\u010denina se skl\u00e1d\u00e1 ze sekvence D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2, ve kter\u00e9 nep\u0159irozen\u00e9 D-aminokyseliny a modifikovan\u00fd zbytek naftylalaninu zaji\u0161\u0165uj\u00ed vysokou stabilitu a silnou afinitu k c\u00edlov\u00e9mu receptoru. Na rozd\u00edl od analogu hormonu uvol\u0148uj\u00edc\u00edho r\u016fstov\u00fd hormon (GHRH) p\u016fsob\u00ed GHRP-2 prost\u0159ednictv\u00edm ghrelinov\u00e9ho receptoru GHSR-1a \u2013 stejn\u00e9ho receptoru, na kter\u00fd se v\u00e1\u017ee t\u011blesn\u00fd hormon ghrelin. V d\u016fsledku toho je GHRP-2 v literatu\u0159e tak\u00e9 popisov\u00e1n jako ghrelinov\u00e9 mimetikum: mal\u00e1 molekula, kter\u00e1 napodobuje vazebn\u00e9 m\u00edsto v\u011bt\u0161\u00ed p\u0159irozen\u00e9 sign\u00e1ln\u00ed molekuly.<\/p>\n<p>D\u00edky t\u00e9to selektivit\u011b receptor\u016f je GHRP-2 \u0161iroce pou\u017e\u00edvanou referen\u010dn\u00ed slou\u010deninou v preklinick\u00fdch a analytick\u00fdch prac\u00edch. V\u00fdzkumn\u00edci ji pou\u017e\u00edvaj\u00ed k charakterizaci vazby na receptory, ke studiu p\u0159enosu sign\u00e1lu cestou GHSR-1a a k jej\u00edmu srovn\u00e1n\u00ed s nov\u00fdmi sekretagogy. Jej\u00ed relativn\u011b kr\u00e1tk\u00fd biologick\u00fd polo\u010das a dobr\u00e1 rozpustnost po rekonstituci ji \u010din\u00ed praktickou pro manipulaci v kontrolovan\u00fdch laboratorn\u00edch podm\u00ednk\u00e1ch.<\/p>\n<h2>Oblasti v\u00fdzkumu<\/h2>\n<p>Ve v\u011bdeck\u00e9 literatu\u0159e se GHRP-2 vyskytuje p\u0159edev\u0161\u00edm v n\u00e1sleduj\u00edc\u00edch v\u00fdzkumn\u00fdch kontextech:<\/p>\n<ul>\n<li>Farmakologie ghrelinov\u00e9ho receptoru (GHSR-1a): vazebn\u00e1 afinita, aktivace receptoru a signalizace downstream v bun\u011b\u010dn\u00fdch modelech.<\/li>\n<li>Regulace pulsatiln\u00edho uvol\u0148ov\u00e1n\u00ed r\u016fstov\u00e9ho hormonu hypof\u00fdzy v preklinick\u00fdch modelech.<\/li>\n<li>Sign\u00e1ln\u00ed osa r\u016fstov\u00e9ho hormonu\/IGF-1 a mechanismy zp\u011btn\u00e9 vazby, kter\u00e9 tuto osu \u0159\u00edd\u00ed.<\/li>\n<li>Neuroendokrinn\u00ed regulace na rozhran\u00ed hypotalamu a hypof\u00fdzy, v\u010detn\u011b interakc\u00ed s endogenn\u00edm ghrelinem.<\/li>\n<li>Vztahy mezi strukturou a aktivitou (SAR): jak D-aminokyseliny a aromatick\u00e9 zbytky ovliv\u0148uj\u00ed stabilitu a vazbu peptidov\u00fdch sekretagog\u016f na receptory.<\/li>\n<li>Srovn\u00e1vac\u00ed v\u00fdzkum s jin\u00fdmi sekretagogy a jako analytick\u00fd referen\u010dn\u00ed standard v metod\u00e1ch HPLC a hmotnostn\u00ed spektrometrie.<\/li>\n<\/ul>\n<h2>GHRP-2 ve srovn\u00e1n\u00ed s p\u0159\u00edbuzn\u00fdmi slou\u010deninami<\/h2>\n<p>GHRP-2 pat\u0159\u00ed do \u0161ir\u0161\u00ed rodiny peptidov\u00fdch sekretagog\u016f, kter\u00e9 v\u0161echny p\u016fsob\u00ed prost\u0159ednictv\u00edm ghrelinov\u00e9ho receptoru, ale li\u0161\u00ed se od sebe strukturou, \u00fa\u010dinnost\u00ed a receptorov\u00fdm profilem. Nejbl\u00ed\u017ee p\u0159\u00edbuzn\u00fd je <a href=\"https:\/\/lumopeptides.com\/product\/ghrp-6\/\" target=\"_blank\" rel=\"noopener\">GHRP-6 10 mg<\/a>, p\u016fvodn\u00ed hexapeptidov\u00fd sekretagog, z n\u011bho\u017e tato s\u00e9rie vze\u0161la; GHRP-2 je jeho struktur\u00e1ln\u011b optimalizovan\u00e1 varianta. <a href=\"https:\/\/lumopeptides.com\/product\/ipamorelin\/\" target=\"_blank\" rel=\"noopener\">Ipamorelin 10 mg<\/a> je \u010dasto citov\u00e1n ve srovn\u00e1vac\u00edch studi\u00edch, proto\u017ee je pova\u017eov\u00e1n za selektivn\u011bj\u0161\u00ed pro cestu pod\u00e1v\u00e1n\u00ed r\u016fstov\u00e9ho hormonu, zat\u00edmco <a href=\"https:\/\/lumopeptides.com\/product\/hexarelin\/\" target=\"_blank\" rel=\"noopener\">Hexarelin 10 mg<\/a> je bl\u00edzce p\u0159\u00edbuzn\u00fd, siln\u00fd hexapeptid, kter\u00fd tak\u00e9 c\u00edl\u00ed na receptor GHSR-1a.<\/p>\n<p>Krom\u011b t\u011bchto agonist\u016f ghrelinov\u00fdch receptor\u016f je GHRP-2 v r\u016fzn\u00fdch studi\u00edch \u010dasto kombinov\u00e1n s analogem GHRH, jako nap\u0159\u00edklad <a href=\"https:\/\/lumopeptides.com\/product\/cjc-1295-no-dac\/\" target=\"_blank\" rel=\"noopener\">CJC-1295 bez DAC 10 mg<\/a>Tyto dva mechanismy \u2013 ghrelinov\u00fd receptor versus GHRH receptor \u2013 jsou v literatu\u0159e zkoum\u00e1ny jako komplement\u00e1rn\u00ed c\u00edle na ose r\u016fstov\u00e9ho hormonu. Takov\u00e1 srovn\u00e1n\u00ed pom\u00e1haj\u00ed p\u0159esn\u011bji zmapovat roli ka\u017ed\u00e9 jednotliv\u00e9 molekuly v neuroendokrinn\u00ed signalizaci.<\/p>\n<h2>Specifikace<\/h2>\n<table>\n<thead>\n<tr>\n<th>Specifikace<\/th>\n<th>Hodnota<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Ochutnat<\/td>\n<td>GHRP-2 (Pralmorelin)<\/td>\n<\/tr>\n<tr>\n<td>Synonyma<\/td>\n<td>Peptid uvol\u0148uj\u00edc\u00ed r\u016fstov\u00fd hormon-2, Pralmorelin, KP-102<\/td>\n<\/tr>\n<tr>\n<td>\u010c\u00edslo CAS<\/td>\n<td>158861-67-7<\/td>\n<\/tr>\n<tr>\n<td>Molekul\u00e1rn\u00ed vzorec \/ hmotnost<\/td>\n<td>C\u2084\u2085H\u2085\u2085N\u2089O\u2086 \/ 817,9 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>PubChem CID<\/td>\n<td>6918245<\/td>\n<\/tr>\n<tr>\n<td>Sekvence<\/td>\n<td>D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2<\/td>\n<\/tr>\n<tr>\n<td>Formul\u00e1\u0159<\/td>\n<td>10 mg lyofilizovan\u00e9ho pr\u00e1\u0161ku (such\u00e9ho pr\u00e1\u0161ku) v jedn\u00e9 lahvi\u010dce<\/td>\n<\/tr>\n<tr>\n<td>\u010cistota<\/td>\n<td>\u2265 99 % (HPLC)<\/td>\n<\/tr>\n<tr>\n<td>Skladov\u00e1n\u00ed<\/td>\n<td>Uchov\u00e1vejte v chladni\u010dce, chra\u0148te p\u0159ed sv\u011btlem a vlhkost\u00ed<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Tvar, manipulace a skladov\u00e1n\u00ed<\/h2>\n<p>GHRP-2 se dod\u00e1v\u00e1 jako steriln\u00ed lyofilizovan\u00fd pr\u00e1\u0161ek (lyofiliz\u00e1t) v 10mg lahvi\u010dce. V lyofilizovan\u00e9 form\u011b je peptid stabiln\u00ed; uzav\u0159enou lahvi\u010dku uchov\u00e1vejte v chladni\u010dce a chra\u0148te p\u0159ed sv\u011btlem a vlhkost\u00ed. Pro pou\u017eit\u00ed ve v\u00fdzkumn\u00e9m prost\u0159ed\u00ed se lyofiliz\u00e1t rozpust\u00ed (rekonstituuje) ve vhodn\u00e9m rozpou\u0161t\u011bdle, pot\u00e9 se roztok uchov\u00e1v\u00e1 v chladni\u010dce a pou\u017e\u00edv\u00e1 se po omezenou dobu, aby se omezila degradace. Pracujte s \u010dist\u00fdm vybaven\u00edm a vyvarujte se opakovan\u00fdch zm\u011bn teploty. Tyto pokyny pro manipulaci plat\u00ed v\u00fdhradn\u011b pro laboratorn\u00ed kontext a nep\u0159edstavuj\u00ed n\u00e1vod k pou\u017eit\u00ed u lid\u00ed ani zv\u00ed\u0159at.<\/p>\n<h2>\u010cistota a laboratorn\u00ed v\u00fdsledky<\/h2>\n<p>GHRP-2 je nab\u00edzen s kontrolovanou \u010distotou \u2265 99 %, stanovenou pomoc\u00ed HPLC. Aktu\u00e1ln\u00ed p\u0159ehled dostupn\u00fdch certifik\u00e1t\u016f anal\u00fdz a laboratorn\u00edch v\u00fdsledk\u016f naleznete na na\u0161ich webov\u00fdch str\u00e1nk\u00e1ch. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">str\u00e1nka s v\u00fdsledky laboratorn\u00edch test\u016f<\/a>Naleznete zde dokumentaci doprov\u00e1zej\u00edc\u00ed na\u0161i \u0159adu v\u00fdzkumn\u00fdch kontakt\u016f.<\/p>\n<h2>\u010casto kladen\u00e9 ot\u00e1zky<\/h2>\n<p><strong>Co p\u0159esn\u011b je GHRP-2?<\/strong><br \/>Jedn\u00e1 se o syntetick\u00fd hexapeptid a agonista ghrelinov\u00e9ho receptoru (GHSR-1a), kter\u00fd je ve v\u011bdeck\u00e9m v\u00fdzkumu studov\u00e1n jako modelov\u00e1 slou\u010denina pro sekretagogy r\u016fstov\u00e9ho hormonu.<\/p>\n<p><strong>Jak\u00fd je rozd\u00edl mezi GHRP-2 a GHRP-6?<\/strong><br \/>Oba jsou hexapeptidov\u00e9 sekretagogy, kter\u00e9 p\u016fsob\u00ed prost\u0159ednictv\u00edm stejn\u00e9ho ghrelinov\u00e9ho receptoru; GHRP-2 je struktur\u00e1ln\u011b optimalizovan\u00e1 varianta. V komparativn\u00edm v\u00fdzkumu jsou porovn\u00e1v\u00e1ny jejich receptorov\u00e9 profily.<\/p>\n<p><strong>Jak se GHRP-2 li\u0161\u00ed od analogu GHRH?<\/strong><br \/>Analog GHRH, jako je CJC-1295, p\u016fsob\u00ed prost\u0159ednictv\u00edm receptoru GHRH, zat\u00edmco GHRP-2 p\u016fsob\u00ed prost\u0159ednictv\u00edm ghrelinov\u00e9ho receptoru GHSR-1a. Tyto dv\u011b dr\u00e1hy jsou v literatu\u0159e pops\u00e1ny jako komplement\u00e1rn\u00ed mechanismy na ose r\u016fstov\u00e9ho hormonu.<\/p>\n<p><strong>Jak by se m\u011bl GHRP-2 skladovat?<\/strong><br \/>Lyofilizovan\u00fd pr\u00e1\u0161ek skladujte v chladni\u010dce, chr\u00e1n\u011bn\u00fd p\u0159ed sv\u011btlem a vlhkost\u00ed. Po rekonstituci se roztok uchov\u00e1v\u00e1 v chladni\u010dce a spot\u0159ebuje se b\u011bhem kr\u00e1tk\u00e9 doby.<\/p>\n<p class=\"lumo-blogcta\"><strong>Chcete se dozv\u011bd\u011bt v\u00edce?<\/strong> P\u0159e\u010dt\u011bte si na\u0161eho pr\u016fvodce: <a href=\"https:\/\/lumopeptides.com\/hgh-peptiden-ghrh-ghrp-uitgelegd\/\" target=\"_blank\" rel=\"noopener\">Vysv\u011btlen\u00ed peptid\u016f HGH: analogy GHRH, GHRP a rozd\u00edl od skute\u010dn\u00e9ho r\u016fstov\u00e9ho hormonu<\/a>.<\/p>\n<p><em>Ur\u010deno v\u00fdhradn\u011b pro laboratorn\u00ed a v\u00fdzkumn\u00e9 \u00fa\u010dely. Nen\u00ed ur\u010deno k lidsk\u00e9 ani zv\u00ed\u0159ec\u00ed spot\u0159eb\u011b, ani k l\u00e9ka\u0159sk\u00e9mu, diagnostick\u00e9mu, terapeutick\u00e9mu nebo kosmetick\u00e9mu pou\u017eit\u00ed. Kupuj\u00edc\u00ed je star\u0161\u00ed 18 let a potvrzuje kontext v\u00fdzkumu. Nejedn\u00e1 se o l\u00e9\u010div\u00fd p\u0159\u00edpravek.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>GHRP-2 (Pralmorelin) je syntetick\u00fd hexapeptid a agonista ghrelinov\u00e9ho receptoru (GHSR-1a). Je studov\u00e1n jako modelov\u00e1 slou\u010denina ve v\u011bdeck\u00e9m v\u00fdzkumu. Je ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed a v\u00fdzkumn\u00e9 \u00fa\u010dely; nen\u00ed ur\u010den k lidsk\u00e9 ani zv\u00ed\u0159ec\u00ed spot\u0159eb\u011b. Nen\u00ed to l\u00e9\u010div\u00fd p\u0159\u00edpravek ani dopln\u011bk stravy.<\/p>","protected":false},"featured_media":3263,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[124,121],"product_tag":[],"class_list":["post-2975","product","type-product","status-publish","has-post-thumbnail","product_cat-musculoskeletaal-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2975","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/comments?post=2975"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2975\/revisions"}],"predecessor-version":[{"id":3042,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2975\/revisions\/3042"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/media\/3263"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/media?parent=2975"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_brand?post=2975"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_cat?post=2975"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_tag?post=2975"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}