{"id":2962,"date":"2026-09-01T09:40:04","date_gmt":"2026-09-01T09:40:04","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2962"},"modified":"2026-09-02T16:15:02","modified_gmt":"2026-09-02T16:15:02","slug":"cjc-1295-zonder-dac-ipamorelin","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/cs\/product\/cjc-1295-zonder-dac-ipamorelin\/","title":{"rendered":"CJC-1295 bez DAC + Ipamorelin"},"content":{"rendered":"<p>Ten\/Ta\/To <strong>CJC-1295 bez DAC + Ipamorelin<\/strong>-blend je p\u0159edem sm\u00edchan\u00e1 kombinovan\u00e1 lahvi\u010dka, ve kter\u00e9 jsou dva sekretagogy r\u016fstov\u00e9ho hormonu (molekuly stimuluj\u00edc\u00ed uvol\u0148ov\u00e1n\u00ed) zkombinov\u00e1ny v pevn\u00e9m pom\u011bru 1:1: CJC-1295 bez DAC (Mod GRF 1-29), analog GHRH (analog hormonu uvol\u0148uj\u00edc\u00edho r\u016fstov\u00fd hormon), a Ipamorelin, selektivn\u00ed agonista ghrelinov\u00fdch receptor\u016f. Oba peptidy p\u016fsob\u00ed na hypof\u00fdzu prost\u0159ednictv\u00edm r\u016fzn\u00fdch sign\u00e1ln\u00edch drah a v laboratorn\u00edm v\u00fdzkumu jsou \u010dasto studov\u00e1ny spole\u010dn\u011b. Tento produkt je ur\u010den v\u00fdhradn\u011b pro v\u011bdeck\u00fd v\u00fdzkum.<\/p>\n<h2>Co je v t\u00e9to sm\u011bsi?<\/h2>\n<p>Lahvi\u010dka obsahuje oba peptidy v pom\u011bru 1:1, p\u0159edem zkombinovan\u00e9 tak, aby byly po rekonstituci k dispozici v jednom roztoku. K dispozici jsou dv\u011b koncentrace: <strong>5 mg + 5 mg<\/strong> a <strong>10 mg + 10 mg<\/strong> na lahvi\u010dku.<\/p>\n<ul>\n<li><strong><a href=\"https:\/\/lumopeptides.com\/product\/cjc-1295-no-dac\/\" target=\"_blank\" rel=\"noopener\">CJC-1295 bez DAC (Mod GRF 1-29)<\/a><\/strong> je modifikovan\u00fd fragment 29 aminokyselin GHRH. \u010cty\u0159i aminokyselinov\u00e9 substituce (v pozic\u00edch 2, 8, 15 a 27) \u010din\u00ed molekulu odoln\u011bj\u0161\u00ed v\u016f\u010di enzymatick\u00e9 degradaci ne\u017e nemodifikovan\u00fd GRF(1-29). Ve v\u00fdzkumn\u00fdch modelech je studov\u00e1na jeho vazba na receptor GHRH v hypof\u00fdze.<\/li>\n<li><strong><a href=\"https:\/\/lumopeptides.com\/product\/ipamorelin\/\" target=\"_blank\" rel=\"noopener\">Ipamorelin<\/a><\/strong> je selektivn\u00ed pentapeptid (Aib-His-D-2-Nal-D-Phe-Lys-NH\u2082), kter\u00fd p\u016fsob\u00ed na ghrelin neboli receptor sekretagogu r\u016fstov\u00e9ho hormonu (GHS-R). Ve v\u00fdzkumu je zn\u00e1m\u00fd pro svou selektivitu v\u016f\u010di p\u0159\u00edbuzn\u00fdm sekretagog\u016fm.<\/li>\n<\/ul>\n<h2>Zd\u016fvodn\u011bn\u00ed kombinace ve v\u00fdzkumu<\/h2>\n<p>Tyto dv\u011b slo\u017eky c\u00edl\u00ed na r\u016fzn\u00e9 receptory a sign\u00e1ln\u00ed dr\u00e1hy. Mod GRF 1-29 se v\u00e1\u017ee na receptor GHRH, zat\u00edmco Ipamorelin aktivuje receptor ghrelinu. V preklinick\u00fdch studi\u00edch se toto p\u00e1rov\u00e1n\u00ed pou\u017e\u00edv\u00e1 ke zkoum\u00e1n\u00ed, jak sou\u010dasn\u00e1 aktivace obou drah ovliv\u0148uje pulsatiln\u00ed uvol\u0148ov\u00e1n\u00ed endogenn\u00edho r\u016fstov\u00e9ho hormonu z hypof\u00fdzy. Tato kombinace analogu GHRH a agonisty receptoru ghrelinu je v literatu\u0159e pova\u017eov\u00e1na za klasick\u00fd model pro studium synergie mezi t\u011bmito dv\u011bma drahami uvol\u0148ov\u00e1n\u00ed a n\u00e1slednou osou IGF-1.<\/p>\n<h2>Specifikace<\/h2>\n<p><strong>CJC-1295 bez DAC (Mod GRF 1-29)<\/strong><\/p>\n<table>\n<thead>\n<tr>\n<th>Specifikace<\/th>\n<th>Hodnota<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Ochutnat<\/td>\n<td>CJC-1295 bez DAC (Mod GRF 1-29)<\/td>\n<\/tr>\n<tr>\n<td>Synonyma<\/td>\n<td>Modifikovan\u00fd GRF (1-29); tetrasubstituovan\u00fd GRF (1-29); bez CJC-1295 DAC<\/td>\n<\/tr>\n<tr>\n<td>Molekul\u00e1rn\u00ed vzorec \/ hmotnost<\/td>\n<td>C\u2081\u2085\u2082H\u2082\u2085\u2082N\u2084\u2084O\u2084\u2082 \/ \u00b1 3367,9 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>Aminokyseliny<\/td>\n<td>29 (modifikovan\u00fd fragment GRF)<\/td>\n<\/tr>\n<tr>\n<td>Formul\u00e1\u0159<\/td>\n<td>Lyofilizovan\u00fd pr\u00e1\u0161ek \u2013 5 mg nebo 10 mg na lahvi\u010dku<\/td>\n<\/tr>\n<tr>\n<td>\u010cistota<\/td>\n<td>\u2265 99 % (HPLC)<\/td>\n<\/tr>\n<tr>\n<td>Skladov\u00e1n\u00ed<\/td>\n<td>Chladno a tma; dlouhodob\u011b p\u0159i \u221220 \u00b0C<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Ipamorelin<\/strong><\/p>\n<table>\n<thead>\n<tr>\n<th>Specifikace<\/th>\n<th>Hodnota<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Ochutnat<\/td>\n<td>Ipamorelin<\/td>\n<\/tr>\n<tr>\n<td>Synonyma<\/td>\n<td>NNC 26-0161<\/td>\n<\/tr>\n<tr>\n<td>\u010c\u00edslo CAS<\/td>\n<td>170851-70-4<\/td>\n<\/tr>\n<tr>\n<td>Molekul\u00e1rn\u00ed vzorec \/ hmotnost<\/td>\n<td>C\u2083\u2088H\u2084\u2089N\u2089O\u2085 \/ 711,9 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>PubChem CID<\/td>\n<td>9831659<\/td>\n<\/tr>\n<tr>\n<td>Sekvence<\/td>\n<td>Aib-His-D-2-Nal-D-Phe-Lys-NH\u2082<\/td>\n<\/tr>\n<tr>\n<td>Formul\u00e1\u0159<\/td>\n<td>Lyofilizovan\u00fd pr\u00e1\u0161ek \u2013 5 mg nebo 10 mg na lahvi\u010dku<\/td>\n<\/tr>\n<tr>\n<td>\u010cistota<\/td>\n<td>\u2265 99 % (HPLC)<\/td>\n<\/tr>\n<tr>\n<td>Skladov\u00e1n\u00ed<\/td>\n<td>Chladno a tma; dlouhodob\u011b p\u0159i \u221220 \u00b0C<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Tvar, manipulace a skladov\u00e1n\u00ed<\/h2>\n<p>Dod\u00e1v\u00e1 se jako lyofilizovan\u00fd (lyofilizovan\u00fd) b\u00edl\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 lahvi\u010dce. Neotev\u0159enou lahvi\u010dku skladujte na chladn\u00e9m a tmav\u00e9m m\u00edst\u011b; pro del\u0161\u00ed skladov\u00e1n\u00ed je ve v\u00fdzkumn\u00e9m prost\u0159ed\u00ed b\u011b\u017en\u00e9 skladov\u00e1n\u00ed p\u0159i teplot\u011b -20 \u00b0C. Po rekonstituci vhodn\u00fdm rozpou\u0161t\u011bdlem skladujte lahvi\u010dku v chladni\u010dce (2\u20138 \u00b0C) a chra\u0148te p\u0159ed sv\u011btlem. S materi\u00e1lem manipulujte v\u00fdhradn\u011b s pou\u017eit\u00edm vhodn\u00e9ho laboratorn\u00edho vybaven\u00ed a v souladu s platn\u00fdmi bezpe\u010dnostn\u00edmi p\u0159edpisy.<\/p>\n<h2>\u010cistota a laboratorn\u00ed v\u00fdsledky<\/h2>\n<p>Oba peptidy jsou nab\u00edzeny s kontrolovanou \u010distotou \u2265 99 %. Analytick\u00e9 certifik\u00e1ty a odpov\u00eddaj\u00edc\u00ed laboratorn\u00ed v\u00fdsledky jsou k dispozici na na\u0161ich webov\u00fdch str\u00e1nk\u00e1ch. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">str\u00e1nka s v\u00fdsledky laboratorn\u00edch test\u016f<\/a>.<\/p>\n<h2>\u010casto kladen\u00e9 ot\u00e1zky<\/h2>\n<p><strong>Co znamen\u00e1 \u201ebez DAC\u201c?<\/strong> DAC (Drug Affinity Complex) je p\u0159\u00edsada, kter\u00e1 prodlu\u017euje dobu ob\u011bhu CJC-1295 v modelech. Ve variant\u011b bez DAC tato p\u0159\u00edsada chyb\u00ed, co\u017e zp\u016fsobuje, \u017ee profil se bl\u00ed\u017e\u00ed profilu nezpracovan\u00e9ho fragmentu GRF(1-29). Ti, kte\u0159\u00ed hledaj\u00ed variantu s dlouhodob\u00fdm \u00fa\u010dinkem, ji najdou jako... <a href=\"https:\/\/lumopeptides.com\/product\/cjc-1295-met-dac\/\" target=\"_blank\" rel=\"noopener\">CJC-1295 s DAC<\/a>.<\/p>\n<p><strong>Pro\u010d jsou tyto dva nab\u00edzeny spole\u010dn\u011b?<\/strong> Proto\u017ee p\u016fsob\u00ed prost\u0159ednictv\u00edm r\u016fzn\u00fdch receptor\u016f, jsou ve v\u00fdzkumu \u010dasto studov\u00e1ny jako p\u00e1r. Podobn\u00e9 uspo\u0159\u00e1d\u00e1n\u00ed s analogem GHRH a agonistou ghrelinov\u00e9ho receptoru je... <a href=\"https:\/\/lumopeptides.com\/product\/tesamorelin-11mg-ipamorelin-6mg\/\" target=\"_blank\" rel=\"noopener\">Tesamorelin + Ipamorelin<\/a>-sm\u011bs.<\/p>\n<p><strong>Jak se pr\u00e1\u0161ek rekonstituuje?<\/strong> Rekonstituce ve v\u00fdzkumn\u00fdch za\u0159\u00edzen\u00edch se obvykle prov\u00e1d\u00ed pomoc\u00ed bakteriostatick\u00e9 vody, kter\u00e1 se pomalu p\u0159id\u00e1v\u00e1 ke st\u011bn\u011b lahvi\u010dky. Net\u0159epe se; pr\u00e1\u0161ek se pomalu rozpou\u0161t\u00ed do \u010dir\u00e9ho roztoku.<\/p>\n<p class=\"lumo-blogcta\"><strong>Chcete se dozv\u011bd\u011bt v\u00edce?<\/strong> P\u0159e\u010dt\u011bte si na\u0161eho pr\u016fvodce: <a href=\"https:\/\/lumopeptides.com\/hgh-peptiden-ghrh-ghrp-uitgelegd\/\" target=\"_blank\" rel=\"noopener\">Vysv\u011btlen\u00ed peptid\u016f HGH: analogy GHRH, GHRP a rozd\u00edl od skute\u010dn\u00e9ho r\u016fstov\u00e9ho hormonu<\/a>.<\/p>\n<p><em>Ur\u010deno v\u00fdhradn\u011b pro laboratorn\u00ed a v\u00fdzkumn\u00e9 \u00fa\u010dely. Nen\u00ed ur\u010deno k lidsk\u00e9 ani zv\u00ed\u0159ec\u00ed spot\u0159eb\u011b, ani k l\u00e9ka\u0159sk\u00e9mu, diagnostick\u00e9mu, terapeutick\u00e9mu nebo kosmetick\u00e9mu pou\u017eit\u00ed. Kupuj\u00edc\u00ed je star\u0161\u00ed 18 let a potvrzuje kontext v\u00fdzkumu. Nejedn\u00e1 se o l\u00e9\u010div\u00fd p\u0159\u00edpravek.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p><strong data-start=\"671\" data-end=\"751\">CJC-1295 bez DAC + Ipamorelin \u2013 Kombinace peptid\u016f pro v\u00fdzkumn\u00e9 aplikace<\/strong><br data-start=\"751\" data-end=\"754\" \/>CJC-1295 bez DAC a Ipamorelin spole\u010dn\u011b tvo\u0159\u00ed syntetickou peptidovou kombinaci pou\u017e\u00edvanou v laboratorn\u00edch a preklinick\u00fdch v\u00fdzkumn\u00fdch prost\u0159ed\u00edch. Ob\u011b molekuly se pou\u017e\u00edvaj\u00ed ve studi\u00edch zam\u011b\u0159en\u00fdch na interakce receptor\u016f a sign\u00e1ln\u00ed dr\u00e1hy. Tato kombinace nen\u00ed ur\u010dena jako l\u00e9ka\u0159sk\u00fd, terapeutick\u00fd ani spot\u0159ebn\u00ed produkt a pou\u017e\u00edvaj\u00ed ji v\u00fdhradn\u011b odborn\u00edci ve v\u00fdzkumn\u00e9m prost\u0159ed\u00ed.<\/p>","protected":false},"featured_media":3317,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[129,124],"product_tag":[],"class_list":["post-2962","product","type-product","status-publish","has-post-thumbnail","product_cat-blends","product_cat-musculoskeletaal-onderzoek","first","instock","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2962","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/comments?post=2962"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2962\/revisions"}],"predecessor-version":[{"id":3033,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2962\/revisions\/3033"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/media\/3317"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/media?parent=2962"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_brand?post=2962"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_cat?post=2962"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_tag?post=2962"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}