{"id":2797,"date":"2026-09-01T09:27:36","date_gmt":"2026-09-01T09:27:36","guid":{"rendered":"https:\/\/pevropeptides.com\/?post_type=product&#038;p=2797"},"modified":"2026-09-02T12:14:49","modified_gmt":"2026-09-02T12:14:49","slug":"kisspeptin-vial-10-mg","status":"publish","type":"product","link":"https:\/\/pevropeptides.com\/cs\/product\/kisspeptin-vial-10-mg\/","title":{"rendered":"Kisspeptin v lahvi\u010dce 10 mg"},"content":{"rendered":"<p>Kisspeptin-10 (KP-10) je minim\u00e1ln\u011b aktivn\u00ed C-termin\u00e1ln\u00ed dekapeptidov\u00fd fragment endogenn\u00edho kisspeptinu, proteinu k\u00f3dovan\u00e9ho genem KISS1. Jako ligand receptoru GPR54 (KISS1R) je kisspeptin v endokrinologii pova\u017eov\u00e1n za centr\u00e1ln\u00ed upstreamov\u00fd regul\u00e1tor hypotalamo-hypofyz\u00e1rn\u011b-gon\u00e1dov\u00e9 osy (osa HPG). Lumo Peptides nab\u00edz\u00ed Kisspeptin-10 v\u00fdhradn\u011b jako lyofiliz\u00e1t (lyofiliz\u00e1t su\u0161en\u00fd pr\u00e1\u0161ek) v\u00fdzkumn\u00e9 kvality pro laboratorn\u00ed a preklinick\u00fd v\u00fdzkum \u2013 nikoli pro pou\u017eit\u00ed u lid\u00ed ani zv\u00ed\u0159at.<\/p>\n<h2>Co je Kisspeptin-10?<\/h2>\n<p>Kisspeptin se v t\u011ble tvo\u0159\u00ed jako v\u011bt\u0161\u00ed prekurzorov\u00fd protein, kter\u00fd se n\u00e1sledn\u011b \u0161t\u011bp\u00ed na krat\u0161\u00ed, biologicky aktivn\u00ed fragmenty. Nejkrat\u0161\u00ed fragment, kter\u00fd st\u00e1le dok\u00e1\u017ee pln\u011b aktivovat receptor, je \u0159et\u011bzec deseti aminokyselin: Kisspeptin-10. Sekvence (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2) odpov\u00edd\u00e1 aminokyselin\u00e1m 45\u201354 molekuly metastinu, a proto se tato slou\u010denina v literatu\u0159e ozna\u010duje tak\u00e9 jako \u201eMetastin (45-54)\u201c nebo jednodu\u0161e \u201eKP-10\u201c.<\/p>\n<p>Ve v\u00fdzkumn\u00fdch modelech se Kisspeptin-10 v\u00e1\u017ee na receptor KISS1R (GPR54) na neuronech GnRH v hypotalamu. Tato interakce receptor-ligand je kl\u00ed\u010dov\u00e1 pro studium neuroendokrinn\u00ed kontroly reproduk\u010dn\u00ed osy: signalizace kisspeptinu je pova\u017eov\u00e1na za jeden z kl\u00ed\u010dov\u00fdch \u010dl\u00e1nk\u016f p\u0159ed hormonem uvol\u0148uj\u00edc\u00edm gonadotropin (GnRH, hormon stimuluj\u00edc\u00ed uvol\u0148ov\u00e1n\u00ed). Jako syntetick\u00fd peptid umo\u017e\u0148uje Kisspeptin-10 studovat tuto dr\u00e1hu kontrolovan\u00fdm a reprodukovateln\u00fdm zp\u016fsobem in vitro a v preklinick\u00fdch modelech, ani\u017e by se spol\u00e9hal na kompletn\u00ed, m\u00e9n\u011b stabiln\u00ed prekurzorov\u00fd protein.<\/p>\n<h2>Oblasti v\u00fdzkumu<\/h2>\n<p>Kisspeptin-10 se ve v\u011bdeck\u00e9 literatu\u0159e objevuje jako pom\u016fcka pro v\u00fdzkum r\u016fzn\u00fdch molekul\u00e1rn\u00edch a fyziologick\u00fdch ot\u00e1zek. P\u0159\u00edklady v\u00fdzkumn\u00fdch sm\u011br\u016f, ve kter\u00fdch tento peptid hraje roli:<\/p>\n<ul>\n<li>Charakterizace receptoru KISS1R\/GPR54 a jeho vazebn\u00e9ho a sign\u00e1ln\u00edho transduk\u010dn\u00edho chov\u00e1n\u00ed v bun\u011b\u010dn\u00fdch modelech.<\/li>\n<li>V\u00fdzkum neuroendokrinn\u00ed regulace hypotalamo-hypofyz\u00e1rn\u011b-gon\u00e1dov\u00e9 osy v preklinick\u00fdch podm\u00ednk\u00e1ch.<\/li>\n<li>Studie sign\u00e1ln\u00ed kask\u00e1dy kisspeptin-GnRH a n\u00e1sledn\u00e9ho uvol\u0148ov\u00e1n\u00ed gonadotropin\u016f na zv\u00ed\u0159ec\u00edch modelech.<\/li>\n<li>Reproduk\u010dn\u00ed endokrinologick\u00fd v\u00fdzkum regulace puberty a cyklick\u00fdch hormon\u00e1ln\u00edch vzorc\u016f.<\/li>\n<li>Studie desenzibilizace receptor\u016f a pom\u011br\u016f d\u00e1vka-odezva p\u0159i opakovan\u00e9 expozici peptid\u016fm.<\/li>\n<li>Srovn\u00e1vac\u00ed studie s p\u0159\u00edbuzn\u00fdmi fragmenty (jako jsou KP-54 a KP-13) za \u00fa\u010delem zmapov\u00e1n\u00ed vztah\u016f mezi strukturou a aktivitou.<\/li>\n<\/ul>\n<h2>Kisspeptin-10 ve srovn\u00e1n\u00ed s p\u0159\u00edbuzn\u00fdmi slou\u010deninami<\/h2>\n<p>V r\u00e1mci v\u00fdzkumu HPG osy je kisspeptin-10 \u010dasto \u0159azen vedle dal\u0161\u00edch regula\u010dn\u00edch peptid\u016f, kter\u00e9 p\u016fsob\u00ed na r\u016fzn\u00fdch \u00farovn\u00edch t\u00e9\u017ee osy. Pokud kisspeptin stoj\u00ed na vrcholu kask\u00e1dy, funguje... <a href=\"https:\/\/lumopeptides.com\/product\/gonadorelin\/\" target=\"_blank\" rel=\"noopener\">Gonadorelin 2 mg<\/a> \u2014 syntetick\u00fd GnRH \u2014 o stupe\u0148 ni\u017e\u0161\u00ed a c\u00edl\u00ed p\u0159\u00edmo na hypof\u00fdzu. <a href=\"https:\/\/lumopeptides.com\/product\/triptorelin\/\" target=\"_blank\" rel=\"noopener\">Triptorelin 2 mg<\/a> je agonista GnRH, kter\u00fd se ve v\u00fdzkumu konkr\u00e9tn\u011b pou\u017e\u00edv\u00e1 k modulaci osy prost\u0159ednictv\u00edm dlouhodob\u00e9 obsazenosti receptor\u016f, zat\u00edmco <a href=\"https:\/\/lumopeptides.com\/product\/hcg\/\" target=\"_blank\" rel=\"noopener\">HCG<\/a> jako analog gonadotropinu p\u016fsob\u00ed je\u0161t\u011b d\u00e1le po proudu. Pro experiment\u00e1ln\u00ed uspo\u0159\u00e1d\u00e1n\u00ed s formou pod\u00e1v\u00e1n\u00ed nosn\u00edho spreje je stejn\u00e1 l\u00e9\u010div\u00e1 l\u00e1tka k dispozici tak\u00e9 jako <a href=\"https:\/\/lumopeptides.com\/product\/kisspeptin-neusspray-kit-10mg\/\" target=\"_blank\" rel=\"noopener\">Kisspeptin nosn\u00ed sprej<\/a>Tato spojen\u00ed dohromady umo\u017e\u0148uj\u00ed porovn\u00e1n\u00ed osy \u0161\u00ed\u0159en\u00ed na v\u00edce \u00farovn\u00edch.<\/p>\n<h2>Specifikace<\/h2>\n<table>\n<thead>\n<tr>\n<th>Specifikace<\/th>\n<th>Hodnota<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Ochutnat<\/td>\n<td>Kisspeptin-10 (KP-10)<\/td>\n<\/tr>\n<tr>\n<td>Synonyma<\/td>\n<td>Metastin (45-54), KP-10, Kisspeptin dekapeptid<\/td>\n<\/tr>\n<tr>\n<td>\u010c\u00edslo CAS<\/td>\n<td>374675-21-5<\/td>\n<\/tr>\n<tr>\n<td>Molekul\u00e1rn\u00ed vzorec \/ hmotnost<\/td>\n<td>C\u2086\u2083H\u2088\u2083N\u2081\u2087O\u2081\u2084 \/ 1302,45 Da<\/td>\n<\/tr>\n<tr>\n<td>PubChem CID<\/td>\n<td>25240297<\/td>\n<\/tr>\n<tr>\n<td>Sekvence<\/td>\n<td>Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2<\/td>\n<\/tr>\n<tr>\n<td>Formul\u00e1\u0159<\/td>\n<td>Lyofilizovan\u00fd pr\u00e1\u0161ek (such\u00fd pr\u00e1\u0161ek), 10 mg na lahvi\u010dku<\/td>\n<\/tr>\n<tr>\n<td>\u010cistota<\/td>\n<td>\u2265 99 % (HPLC)<\/td>\n<\/tr>\n<tr>\n<td>Skladov\u00e1n\u00ed<\/td>\n<td>Uchov\u00e1vejte v chladni\u010dce, chra\u0148te p\u0159ed sv\u011btlem a vlhkost\u00ed<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Tvar, manipulace a skladov\u00e1n\u00ed<\/h2>\n<p>Kisspeptin-10 se dod\u00e1v\u00e1 jako lyofiliz\u00e1t: lyofilizovan\u00fd pr\u00e1\u0161ek o hmotnosti 10 mg na lahvi\u010dku, kter\u00fd je dob\u0159e uchov\u00e1v\u00e1n v suchu a chladni\u010dce. Neotev\u0159en\u00fd pr\u00e1\u0161ek by m\u011bl b\u00fdt nejl\u00e9pe skladov\u00e1n v mrazni\u010dce, chr\u00e1n\u011bn p\u0159ed sv\u011btlem a vlhkost\u00ed. Pro laboratorn\u00ed pou\u017eit\u00ed se lyofiliz\u00e1t rekonstituuje vhodn\u00fdm roztokem, na\u010de\u017e se rozpu\u0161t\u011bn\u00fd peptid uchov\u00e1v\u00e1 v chladni\u010dce (2\u20138 \u00b0C) a kr\u00e1tce se skladuje, aby se omezila degradace. V\u017edy pou\u017e\u00edvejte steriln\u00ed techniky a vyhn\u011bte se opakovan\u00fdm cykl\u016fm zmrazov\u00e1n\u00ed a rozmrazov\u00e1n\u00ed, proto\u017ee by mohly naru\u0161it integritu peptidov\u00e9ho \u0159et\u011bzce.<\/p>\n<p class=\"lumo-blogcta\"><strong>Chcete se dozv\u011bd\u011bt v\u00edce?<\/strong> P\u0159e\u010dt\u011bte si na\u0161eho pr\u016fvodce: <a href=\"https:\/\/lumopeptides.com\/bacteriostatisch-water-waarvoor-gebruik-je-het-en-hoe-meng-je-correct\/\" target=\"_blank\" rel=\"noopener\">Bakteriostatick\u00e1 voda: k \u010demu se pou\u017e\u00edv\u00e1 a jak ji spr\u00e1vn\u011b m\u00edch\u00e1te?<\/a><\/p>\n<h2>\u010cistota a laboratorn\u00ed v\u00fdsledky<\/h2>\n<p>Kisspeptin-10 je nab\u00edzen s kontrolovanou \u010distotou \u2265 99 %, stanovenou pomoc\u00ed HPLC. Pro v\u00fdzkum je nezbytn\u00e1 konzistentn\u00ed, dob\u0159e charakterizovan\u00e1 surovina: ne\u010distoty nebo produkty degradace mohou interferovat s receptorov\u00fdmi experimenty a m\u011b\u0159en\u00edm z\u00e1vislosti d\u00e1vky na odpov\u011bdi. Aktu\u00e1ln\u00ed laboratorn\u00ed dokumentaci k na\u0161im peptid\u016fm naleznete v na\u0161em bal\u00ed\u010dku. <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">str\u00e1nka s v\u00fdsledky laboratorn\u00edch test\u016f<\/a>.<\/p>\n<h2>\u010casto kladen\u00e9 ot\u00e1zky<\/h2>\n<p><strong>Co znamen\u00e1 ozna\u010den\u00ed \u201eKP-10\u201c?<\/strong><br \/>KP-10 je b\u011b\u017en\u00e1 zkratka pro Kisspeptin-10, dekapeptid (deset aminokyselin), kter\u00fd odpov\u00edd\u00e1 C-termin\u00e1ln\u00edmu fragmentu 45\u201354 metastinu. V literatu\u0159e se stejn\u00e1 molekula vyskytuje tak\u00e9 jako \u201eMetastin (45-54)\u201c.<\/p>\n<p><strong>Pro\u010d se dod\u00e1v\u00e1 v lyofilizovan\u00e9 form\u011b?<\/strong><br \/>Lyofilizovan\u00fd pr\u00e1\u0161ek je v\u00fdrazn\u011b stabiln\u011bj\u0161\u00ed ne\u017e roztok p\u0159ipraven\u00fd k pou\u017eit\u00ed. V t\u00e9to form\u011b z\u016fst\u00e1v\u00e1 peptid d\u00e9le neporu\u0161en\u00fd b\u011bhem skladov\u00e1n\u00ed a p\u0159epravy; koncov\u00fd u\u017eivatel jej rekonstituuje pouze t\u011bsn\u011b p\u0159ed anal\u00fdzou.<\/p>\n<p><strong>Jak si Kisspeptin-10 vede v porovn\u00e1n\u00ed s pln\u00fdm kisspeptinem (KP-54)?<\/strong><br \/>KP-54 je del\u0161\u00ed fragment stejn\u00e9ho prekurzorov\u00e9ho proteinu. Kisspeptin-10 je nejkrat\u0161\u00ed fragment, kter\u00fd st\u00e1le dok\u00e1\u017ee pln\u011b aktivovat receptor KISS1R, co\u017e z n\u011bj \u010din\u00ed praktick\u00fd a vysoce reprodukovateln\u00fd model sign\u00e1ln\u00ed dr\u00e1hy kisspeptinu ve v\u00fdzkumu.<\/p>\n<p><strong>Kde najdu doprovodnou laboratorn\u00ed dokumentaci?<\/strong><br \/>Ve\u0161ker\u00e1 laboratorn\u00ed dokumentace v na\u0161em sortimentu je sdru\u017eena na <a href=\"https:\/\/lumopeptides.com\/labresultaten\/\" target=\"_blank\" rel=\"noopener\">str\u00e1nka s v\u00fdsledky laboratorn\u00edch test\u016f<\/a>.<\/p>\n<p><strong>Je tento produkt vhodn\u00fd pro lidsk\u00e9 pou\u017eit\u00ed?<\/strong><br \/>Ne. Kisspeptin-10 je ur\u010den v\u00fdhradn\u011b pro in vitro a preklinick\u00fd laboratorn\u00ed v\u00fdzkum a nen\u00ed ur\u010den k lidsk\u00e9 ani zv\u00ed\u0159ec\u00ed spot\u0159eb\u011b.<\/p>\n<p><em>Ur\u010deno v\u00fdhradn\u011b pro laboratorn\u00ed a v\u00fdzkumn\u00e9 \u00fa\u010dely. Nen\u00ed ur\u010deno k lidsk\u00e9 ani zv\u00ed\u0159ec\u00ed spot\u0159eb\u011b, ani k l\u00e9ka\u0159sk\u00e9mu, diagnostick\u00e9mu, terapeutick\u00e9mu nebo kosmetick\u00e9mu pou\u017eit\u00ed. Kupuj\u00edc\u00ed je star\u0161\u00ed 18 let a potvrzuje kontext v\u00fdzkumu. Nejedn\u00e1 se o l\u00e9\u010div\u00fd p\u0159\u00edpravek.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p class=\"my-2 [&#038;+p]:mt-4 [&#038;_strong:has(+br)]:inline-block [&#038;_strong:has(+br)]:pb-2\"><strong data-start=\"789\" data-end=\"844\">Kisspeptin-10 \u2013 Peptide voor Onderzoekstoepassingen<\/strong><br data-start=\"844\" data-end=\"847\" \/>Kisspeptin-10 is een synthetisch peptide gebaseerd op een kort fragment van een natuurlijk voorkomend eiwit. Het wordt ingezet binnen laboratorium- en preklinische onderzoeksomgevingen waarin peptide-eigenschappen, receptorinteracties en moleculaire stabiliteit worden bestudeerd. Kisspeptin-10 is geen consumentenproduct en is niet bedoeld voor medische, endocriene of fysiologische toepassingen.<\/p>\n","protected":false},"featured_media":3234,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[119,121],"product_tag":[],"class_list":["post-2797","product","type-product","status-publish","has-post-thumbnail","product_cat-hormonaal-onderzoek","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2797","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/comments?post=2797"}],"version-history":[{"count":1,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2797\/revisions"}],"predecessor-version":[{"id":2875,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product\/2797\/revisions\/2875"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/media\/3234"}],"wp:attachment":[{"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/media?parent=2797"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_brand?post=2797"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_cat?post=2797"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pevropeptides.com\/cs\/wp-json\/wp\/v2\/product_tag?post=2797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}